- Antibody type:Primary
- Antigen name:Bcl2-interacting Mediator of Cell Death
- Antigen symbol:BIMS/EL/L
- Clonality:Monoclonal
- Clone:10B12
- Conjugation:Unconjugated
- ELISA:Yes
- Flow cytometry:Yes
- Host:Rat
- ImmunoChemistry:Yes
- ImmunoPrecipitation:Yes
- Isotype:IgG2a kappa
- Reactivity:Monkey,Human,Dog,Rat,Mouse
- Western blot:Yes
- Environmentally Preferable:
- Form:Liquid
- Antigen synonyms:BCL2L11|Bcl-2-like Protein 11
- Storage buffer:In PBS containing 0.02% sodium azide and 25% glycerol.
- Storage temperature:Stable for at least 1 year after receipt when stored at -20˚C.
- Concentration:1 mg/ml
- Shipping temperature:-20°C
- Immunogen:Synthetic peptide corresponding to aa 20-40 of mouse BimL.
- Tested applications:FACS,
- Purification:>95% (SDS-PAGE)
- Size:100 μg
- Pk:100 µG
Bim belongs to the Bcl-2 protein family. Bcl-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein contains a Bcl-2 homology domain 3 (BH3). It has been shown to interact with other members of the Bcl-2 protein family (BCL2, BCL2L1/BCL-X(L) and MCL1) and to act as an apoptotic activator, inducing apoptosis and anoikis. Several variants have been identified. The isoforms vary in cytotoxicity with isoform BimS being the most potent and isoform BimEL being the least potent.
Type: Primary
Antigen: BIMS/EL/L
Clonality: Monoclonal
Clone: 10B12
Conjugation: Unconjugated
Epitope:
Host: Rat
Isotype: IgG2a kappa
Reactivity: Dog, Human, Monkey, Mouse, Rat