Distek, Inc. has developed a benchtop scale single-use bioreactor (SUB) for mammalian cell growth, cell therapy, insect cells, and other unique applications performed in a stirred tank bioreactor. The gamma irradiated BIOne SUB is engineered with a disposable headplate welded to a triple-layered liner that can be easily inserted into a non sterile bioreactor glass vessel, converting it to a disposable SUB within a matter of seconds.

• Customizable above and below the headplate
• 2 and 5 L working volume
• Optional single-use pH probe
• Increased throughput
• Weldable tubing
• Non-invasive DO probe port
• USP class VI materials
• Animal derivative-free and low antioxidant liner material
• Compatible with most manufacturers’ glass vessels and controllers

Upon media addition, the liner expands and molds to the glass vessel, preserving the geometry of the existing bioreactor. The BIOne SUB’s liner material emulates the large-scale SUBs used in pilot and commercial biopharma production facilities around the world. Performing R&D studies using the most similar material on the market streamlines your tech transfer and can de-risk your process before transferring to pilot scale.