- Antibody type:Primary
- Antigen name:Claudin 10
- Clonality:Polyclonal
- Conjugation:Alexa Fluor® 555
- Host:Rabbit
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Isotype:IgG
- Reactivity:Human
- Environmentally Preferable:
- Epitope:151-228/228
- Form:Liquid
- Antigen synonyms:Claudin-10|OSP L|OSP-like protein|OSP like protein|CLDN 10|OSPL|CPETRL3|Claudin10|CLDN10 protein|HGNC:2033|CLDN10|CLD10_HUMAN|CPETRL 3
- Modification:Unmodified
- Storage buffer:Aqueous buffered solution containing 0,01M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol.
- Molecular weight:24 kDa
- Storage temperature:Store at −20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Concentration:1 µg/µl
- Shipping temperature:4 °C
- Immunogen:KLH conjugated synthetic peptide derived from human Claudin 10
- Tested applications:ICC
- Purification:Purified by Protein A
- Pack type:Vial
- Pk:100 µl
The claudin superfamily consists of many structurally related proteins in humans. These proteins are important structural and functional components of tight junctions in paracellular transport. Claudins are located in both epithelial and endothelial cells in all tight junction-bearing tissues. Three classes of proteins are known to localize to tight junctions, including the claudins, Occludin and junction adhesion molecules. Claudins, which consist of four transmembrane domains and two extracellular loops, make up tight junction strands. Claudin expression is often highly restricted to specfic regions of different tissues and may have an important role in transcellular transport through tight junctions. Claudin-10 is a 228 amino acid multi-pass membrane protein that belongs to the claudin family and plays an important role in cell-adhesion activity and tight junction-specific events.
Type: Primary
Antigen: Claudin 10
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 555
Public Immunogen Range: 151-228/228
Host: Rabbit
Isotype: IgG
Reactivity: Human