TSKgel® UP-SW Aggregate, the latest addition to the UP-SW series of silica-based size exclusion chromatography (SEC) columns, are specifically designed to facilitate the analysis of mAb aggregates, high molecular weight (MW) proteins and nulceic acids.

• Optimized for large proteins and higher order mAb aggregates
• Proven TSKgel® SW SEC quality
• Provides high sensitivity and excellent column efficiency
• Compatible with both HPLC and UHPLC systems
• Calibration range (proteins):10 - 2000 kDa

These columns are 3 µm, 30 nm pore size SEC analytical columns, that have been designed with a higher exclusion limit than other TSKgel® UP-SW columns.

Available in 4.6 mm ID, TSKgel® UP-SW Aggregate columns are compatible with both UHPLC and HPLC systems and require less sample while delivering higher sensitivity compared to the 7.8 mm ID TSKgel® UltraSW Aggregate columns.

These columns feature high pore volume, low sample adsorption (due to the derivatization of the particle surface with ligands containing diol functional groups) and excellent column efficiency, all contributing to unsurpassed sample resolution.