- Antigen name:Hypoxanthine phosphoribosyltransferase 1
- Antigen symbol:HPRT1
- Clonality:Monoclonal
- Conjugation:Unconjugated
- ELISA:Yes
- Host:Mouse
- Isotype:IgG2b
- Reactivity:Human
- Western blot:Yes
- Environmentally Preferable:
- Antigen synonyms:HGPRTase|Hypoxanthine-guanine phosphoribosyltransferase|HGPRT|HPRT1|HPRT
- Immunogen:Ni-NTA purified truncated recombinant HPRT expressed in E. Coli strain BL21 (DE3).
- Size:100 µl
- Pk:100 µl
The HPRT1 gene provides instructions for making an enzyme called hypoxanthine phosphoribosyltransferase 1. This enzyme allows cells to recycle purines, some of the building blocks of DNA and its chemical cousin RNA.The enzyme hypoxanthine-guanine phosphoribosyltrasferase (E.C.2.4.2.8., HPRT) plays a crucial role in uric acid synthesis and purine metabolism.This enzyme catalyzes the conversion of hypoxanthine and guanine to inosine monophosphate (IMP) and guanosine monophosphate (GMP), respectively, and uses phosphoribosylpyrophosphate (PRPP) as a cosubstrate and as a source of energy. This pathway is also known as the purine salvage pathway because it allows cells to reuse purine compounds to build DNA and RNA.
Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
Type:
Antigen: HPRT1
Clonality: Monoclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype: IgG2b
Reactivity: Human