About this item
UACA (Uveal Autoantigen with Coiled-coil domains and Ankyrin repeats) is a 1,416 amino acid nuclear membrane protein. It was originally identified as an autoantigen in patients with panuveitis, a characteristic of Vogt-Koyanagi-Harada disease, and in patients with Graves' disease. UACA was also later identified as Nucling, an mRNA differentially expressed in F9 embryonal carcinoma cells during cardiac muscle differentiation. UACA appears to function as a pro-apoptotic protein that recruits the apaf-1-pro-caspase-9 complex for the induction of apoptosis to mediate the cell-death pathway.
Type: Primary
Antigen: UACA
Clonality: Monoclonal
Clone: AE-5
Conjugation: Purified
Epitope:
Host: Mouse
Isotype: IgG1 kappa
Reactivity: Human, Mouse
Specifications
- Catalog No:
- BNUB0956-500
- BNUB0956-100
- Antigen symbol:
- UACA
- UACA
- Antigen name:
- UACA / Nucling
- UACA / Nucling
- Antigen synonyms:
- Uveal autoantigen with coiled-coil domains and ankyrin repeats (UACA)|NUCLING|Nuclear membrane binding protein
- Uveal autoantigen with coiled-coil domains and ankyrin repeats (UACA)|NUCLING|Nuclear membrane binding protein
- Antibody type:
- Primary
- Primary
- Clonality:
- Monoclonal
- Monoclonal
- Conjugation:
- Unconjugated
- Unconjugated
- Clone:
- Clone AE-5
- Clone AE-5
- Reactivity:
- Human, Mouse
- Human, Mouse
- Host:
- Mouse
- Mouse
- Gene ID:
- 108049
- 108049
- Isotype:
- IgG1 kappa
- IgG1 kappa
- Western blot:
- Yes
- Yes
- ImmunoFluorescence:
- Yes
- Yes
- Concentration:
- 0,2 mg/ml
- 0,2 mg/ml
- Storage buffer:
- PBS/0,05% BSA/0,05% azide
- PBS/0,05% BSA/0,05% azide
Specifications
Supplier: HEATHROW
Supplier: VWR Chemicals
Supplier: VWR Chemicals
Supplier: VWR Chemicals
Supplier: VWR Collection
Supplier: VWR Collection
Supplier: VWR Chemicals
Supplier: Merck
Supplier: VWR Collection
Supplier: VWR Collection
Supplier: KIMBERLY CLARK
Supplier: VWR Collection