This antibody recognizes a protein doublet of 20-22 kDa, identified as MART-1 (Melanoma Antigen Recognized by T cells 1) or Melan-A. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Seven other melanoma associated antigens recognized by autologous cytotoxic T cells include MAGE-1, MAGE-3, tyrosinase, gp100, gp75, BAGE-1, and GAGE-1. Subcellular fractionation shows that MART-1 is present in melanosomes and endoplasmic reticulum. This MAb labels melanomas and other tumors showing melanocytic differentiation. It is also a useful positive-marker for angiomyolipomas. It does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin.
Type: Primary
Antigen: MLANA
Clonality: Monoclonal
Clone: MLANA/788
Conjugation: Biotin
Epitope:
Host: Mouse
Isotype: IgG1 kappa
Reactivity: Dog, Human, Mouse, Rat
- Catalog No:
- BNCB0788-500
- BNCB0788-100
- Antigen symbol:
- MLANA
- MLANA
- Antigen name:
- Melan A
- Melan A
- Antigen synonyms:
- MLAN-A|Antigen LB39-AA|Melanoma antigen recognized by T-cells 1|Antigen SK29-AA|MLANA
- MLAN-A|Antigen LB39-AA|Melanoma antigen recognized by T-cells 1|Antigen SK29-AA|MLANA
- Antibody type:
- Primary
- Primary
- Clonality:
- Monoclonal
- Monoclonal
- Conjugation:
- Biotin
- Biotin
- Clone:
- Clone MLANA/788
- Clone MLANA/788
- Reactivity:
- Human, Dog, Rat, Mouse
- Human, Dog, Rat, Mouse
- Host:
- Mouse
- Mouse
- Gene ID:
- 154069
- 154069
- Isotype:
- IgG1 kappa
- IgG1 kappa
- Western blot:
- Yes
- Yes
- ImmunoChemistry:
- Yes
- Yes
- ImmunoFluorescence:
- Yes
- Yes
- Concentration:
- 0,1 mg/ml
- 0,1 mg/ml
- Storage buffer:
- PBS/0,1% BSA/0,05% azide
- PBS/0,1% BSA/0,05% azide
: VWR Chemicals
: VWR Collection
: VWR Collection
: VWR Chemicals
: KIMBERLY CLARK
: VWR Collection
: VWR Collection
: VWR Collection