Recognizes a phosphor-protein of 45 kDa, identified as MyoD1. The epitope of this MAb maps between amino acid 180-189 in the C-terminal of mouse MyoD1 protein. It does not cross react with myogenin, Myf5, or Myf6. Antibody to MyoD1 labels the nuclei of myoblasts in developing muscle tissues. MyoD1 is not detected in normal adult tissue, but is highly expressed in the tumor cell nuclei of rhabdomyosarcomas. Occasionally nuclear expression of MyoD1 is seen in ectomesenchymoma and a subset of Wilm s tumors. Weak cytoplasmic staining is observed in several non-muscle tissues, including glandular epithelium and also in rhabdomyosarcomas, neuroblastomas, Ewing s sarcomas and alveolar soft part sarcomas.
Type: Primary
Antigen: MYOD1
Clonality: Monoclonal
Clone: 5.8A
Conjugation: CF405S
Epitope:
Host: Mouse
Isotype: IgG1 kappa
Reactivity: Chicken, Human, Mouse, Rat
- Catalog No:
- BNC040191-100
- BNC040191-500
- Antigen symbol:
- MYOD1
- MYOD1
- Antigen name:
- MyoD1
- MyoD1
- Antigen synonyms:
- Myogenic differentiation 1|Class C basic helix-loop-helix protein 1|PUM|Myogenin D1|Myogenic factor 3 (Myf-3)|Myoblast determination protein 1|bHLHc1
- Myogenic differentiation 1|Class C basic helix-loop-helix protein 1|PUM|Myogenin D1|Myogenic factor 3 (Myf-3)|Myoblast determination protein 1|bHLHc1
- Antibody type:
- Primary
- Primary
- Clonality:
- Monoclonal
- Monoclonal
- Conjugation:
- CF® 405S
- CF® 405S
- Clone:
- Clone 5.8A
- Clone 5.8A
- Reactivity:
- Chicken, Human, Rat, Mouse
- Chicken, Human, Rat, Mouse
- Host:
- Mouse
- Mouse
- Gene ID:
- 181768
- 181768
- Isotype:
- IgG1 kappa
- IgG1 kappa
- ImmunoChemistry:
- Yes
- Yes
- ImmunoFluorescence:
- Yes
- Yes
- Concentration:
- 0,1 mg/ml
- 0,1 mg/ml
- Storage buffer:
- PBS/0,1% BSA/0,05% azide
- PBS/0,1% BSA/0,05% azide
: VWR Chemicals
: VWR Chemicals
: KIMBERLY CLARK
: VWR Collection
: VWR Collection
: VWR Collection
: VWR Collection
: VWR Collection