- Antibody type:Primary
- Antigen name:Kv1.1 potassium channel
- Antigen symbol:KCNA1
- Clonality:Polyclonal
- Conjugation:Unconjugated
- Host:Rabbit
- ImmunoChemistry:Yes
- Isotype:IgG
- Reactivity:Human,Rat,Mouse
- Western blot:Yes
- Environmentally Preferable:
- Form:liquid
- Antigen synonyms:HUK1|Voltage-gated K+ channel HuKI|EA1|Voltage-gated potassium channel HBK1|AEMK|Kv1.1 potassium channel|Kca1 1|KCNA1_HUMAN|Episodic ataxia with myokymia|HBK1|Potassium voltage gated channel subfamily A member 1|Voltage gated potassium channel subunit Kv1.1|Potassium voltage gated channel shaker related subfamily member 1|Potassium channel protein 1|Kcpvd|MGC124402|Shak|Kcna1|Potassium voltage-gated channel subfamily A member 1|KV1.1|mceph|MK1|MGC138385|RBK1|Shaker related subfamily member 1|MGC126782|Voltage-gated potassium channel subunit Kv1.1.|MBK1
- Storage buffer:Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0,09% sodium azide. Store at -20°C for 12 months.
- Concentration:1 ug/ul
- Shipping temperature:4 °C
- Purification:Purified by Protein A.
- Size:100 μg
- Pk:100 µl
Voltage-gated K+ channels in the plasma membrane control the repolarization and the frequency of action potentials in neurons, muscles, and other excitable cells. The KV gene family encodes more than 30 genes that comprise the subunits of the K+ channels, and they vary in their gating and permeation properties, subcellular distribution, and expression patterns. Functional KV channels assemble as tetramers consisting of pore-forming alpha-subunits (KV alpha), which include the KV1, KV2, KV3, and KV4 proteins, and accessory or KV beta subunits that modify the gating properties of the coexpressed KV alpha subunits. Differences exist in the patterns of trafficking, biosynthetic processing and surface expression of the major KV1 subunits (KV1.1, KV1.2, KV1.4, KV1.5 and KV1.6) expressed in rat and human brain, suggesting that the individual protein subunits are highly regulated to control for the assembly and formation of functional neuronal channels.
WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
Type: Primary
Antigen: Kv1.1
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat