Anti-LRSAM1 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Catalog # BOSSBS-9387R-A488

Supplier: Bioss

Catalog # BOSSBS-9387R-A488

Supplier: Bioss

Specifications

Antibody type:
Primary
Antigen name:
Leucine Rich Repeat And Sterile Alpha Motif Containing 1
Antigen symbol:
LRSAM1
Clonality:
Polyclonal
Conjugation:
Alexa Fluor® 488
Host:
Rabbit
ImmunoChemistry:
Yes
Isotype:
IgG
Reactivity:
Human,
Rat,
Mouse
Environmentally Preferable:
Cross adsorption:
No
Form:
liquid
Gene ID:
90678
Antigen synonyms:
Leucine rich repeat and sterile alpha mot containing protein 1|TAL|CMT2P|E3 ubiquitin protein ligase LRSAM1|hTAL|RIFLE
Storage buffer:
Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
Storage temperature:
Store at –20 °C for 12 months
Concentration:
1 μg/μl
Shipping temperature:
4°C
Purification:
Purified by Protein A
Pk:
100 µl

Specifications

About this item

LRSAM1 is an E3 ubiquitin-protein ligase that mediates monoubiquitination of TSG101 at multiple sites, leading to inactivation of the ability of TSG101 to sort endocytic (EGF receptors) and exocytic (HIV-1 viral proteins) cargos. It selectively regulates cell adhesion molecules and plays a role in receptor endocytosis and viral budding. LRSAM1 contains a RING-type zinc finger, 5 leucine-rich repeats and 1 SAM (sterile alpha motif) domain. The coiled coil domains interact with the SB domain of TSG101. The PTAP motifs mediate the binding to UEV domains. There are 3 isoforms produced by alternative splicing.

Recommended Dilutions: IF(IHC-P): 1:50-200

Type: Primary
Antigen: LRSAM1
Clonality: Polyclonal
Clone:
Conjugation: Alexa Fluor® 488
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat