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Anti-Gemin 4 Rabbit Polyclonal Antibody (Alexa Fluor® 680)
Catalog # BOSSBS-13328R-A680
Supplier:  Bioss
Anti-Gemin 4 Rabbit Polyclonal Antibody (Alexa Fluor® 680)
Catalog # BOSSBS-13328R-A680
Supplier:  Bioss

Specifications

  • Antibody type:
    Primary
  • Antigen name:
    Gemin 4
  • Clonality:
    Polyclonal
  • Conjugation:
    Alexa Fluor® 680
  • Host:
    Rabbit
  • ImmunoChemistry:
    Yes
  • ImmunoFluorescence:
    Yes
  • Isotype:
    IgG
  • Reactivity:
    Human
  • Western blot:
    Yes
  • Environmentally Preferable:
  • Epitope:
    251-350/1058
  • Form:
    Liquid
  • Gene ID:
    50628
  • Antigen synonyms:
    Component of gems 4|Gem associated protein 4|HC56|Gemin-4|HHRF 1|GEMI4_HUMAN|Gemin4
  • Modification:
    Unmodified
  • Storage buffer:
    Aqueous buffered solution containing 0,01M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol.
  • Molecular weight:
    120 kDa
  • Storage temperature:
    Store at −20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
  • Concentration:
    1 µg/µl
  • Shipping temperature:
    4 °C
  • Immunogen:
    KLH conjugated synthetic peptide derived from human Gemin 4
  • Tested applications:
    ICC
  • Purification:
    Purified by Protein A
  • Pack type:
    Vial
  • Pk:
    100 µl

Specifications

About this item

Gemin4 is a component of the SMN core complex which, while in the cytoplasm, plays an essential role in ribonucleoprotein (snRNP) assembly, including the biogenesis, delivery and recycling of snRNPs to the spliceosome. In the nucleus, where SMN is required for pre-mRNA splicing, Gemin4 concentrates next to coiled bodies in subnuclear structures called gems, that are highly enriched in splicosomal snRNPs, and in the nucleolus. Deletion or loss-of-function mutations in the SMN lead to the neurodegenerative disease spinal muscular atrophy (SMA). The human Gemin4 maps to chromosome 17p13.

Type: Primary
Antigen: Gemin 4
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 680
Public Immunogen Range: 251-350/1058
Host: Rabbit
Isotype: IgG
Reactivity: Human