Tris(hydroxymethyl)aminomethane (TRIS, Trometamol) 99.0-101.0% USP, Multi-Compendial, J.T.Baker®

: 2-Amino-2-(hydroxymethyl)propane-1,3-diol(tris), Tromethamine, Tris(hydroxymethyl)methylamine, 2-Amino-2-(hydroxymethyl)propane-1,3-diol, 2-Amino-2-(hydroxymethyl)-1,3-propanediol, Trizma(R) base, TRIS base, THAM

:77-86-1

:NH₂C(CH₂OH)₃

:MFCD00004679

:357

:169…172 °C

:1.328 g/cm³ (20 °C)

:121.14 g/mol

:13,09842

:201-064-4

:GHS07

:Ambient

Environmentally Preferable:

Meets JPC (1997) Chemical Specifications:
99.0 - 101.0%
Meets B.P. Chemical Specifications:
Passes Test
Meets E.P. Chemical Specifications:
Passes Test
Meets U.S.P Requirements:
Passes Test
GMP Manufactured Product:
10.0 - 11.5
CAUTION: For Manufacturing, processing or repackaging:
≤1.0%
Bulk Pharmaceutical Chemical:
≤0.1%
USP - Assay (C₄H₁₁NO₃):
99.0 - 101.0 %
USP - Identification A:
Passes Test
USP - Identification B:
Passes Test
USP - Identification C:
Passes Test
USP - pH (1 in 20):
10.0 - 11.5
USP - Loss on Drying:
≤1.0 %
USP - Residue on Ignition:
≤0.1 %
USP - Melting Range(Lower):
168 - 172 °C
USP - Melting Range(Upper):
168 - 172 °C
EP/BP - Assay (C₄H₁₁NO₃) (dried basis):
99.0 - 100.5 %
EP/BP - Identification B (melting point):
168 - 174 °C
EP/BP - Identification C:
Passes Test
EP/BP - Appearance of Solution:
Passes Test
EP/BP - pH:
10.0 - 11.5
EP/BP - Related Substances:
≤1.0 %
EP/BP - Chloride (Cl):
≤100 ppm
EP/BP - Iron (Fe):
≤10 ppm
EP/BP - Loss on Drying at 105°C:
≤0.5 %
EP/BP - Ash (sulfated):
≤0.1 %
JPC 1997 - Assay (C₄H₁₁NO₃) (dried basis):
≥99.0 %
JPC 1997 - Identification A:
Passes Test
JPC 1997 - Identification B:
Passes Test
JPC 1997 - pH:
10.3 - 10.7
JPC 1997 - Melting Point:
168 - 172 °C
JP - Clarity and Color of Solution:
Passes Test
JPC 1997 - Heavy Metals (as Pb):
≤8 ppm
JPC 1997 - Arsenic (As):
≤1.6 ppm
JPC 1997 - Loss on Drying:
≤0.5 %
JPC 1997 - Residue on Ignition:
≤0.10 %
Assay (C₄H₁₁NO₃) (dried basis):
≥99.9 %
Absorbance of a 1M Solution - 260 nm:
≤0.06
Absorbance of a 1M Solution - 280 nm:
≤0.06
Absorbance of a 1M Solution - 400 nm:
≤0.01
Endotoxin Concentration (EU/g):
≤2.5
Iron (Fe):
≤1 ppm
Lead (Pb):
≤1 ppm

sds_BAKR4102

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