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Human recombinant GMP Reductase 1 (from cells)
Human recombinant GMP Reductase 1 (from cells)
Catalog # PRSI91-666
Supplier:  ProSci Inc.
CAS Number:  
Human recombinant GMP Reductase 1 (from cells)
Catalog # PRSI91-666
Supplier:  ProSci Inc.
CAS Number:  

Specifications

  • Pk:
    50 µG
  • Enzyme type:
    Recombinant
  • Source:
    Cells
  • Species:
    Human
  • Environmentally Preferable:
  • Tag sequence:
    C-6 His tag
  • Storage conditions:
    Store at −20 °C, stable for 6 months after receipt. Please minimize freeze−thaw cycles.
  • Enzyme name:
    GMP Reductase 1
  • Purity:
    >95% as determined by reducing SDS-PAGE
  • Molecular weight:
    38.5 kD
  • Sequence:
    Met1-Ser345
  • Formulation:
    Supplied as a 0.2 µm filtered solution of 20 mM Tris-HCl,40% glycerol,0.15M NaCl and 1 mM DTT, pH 8.0. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH₂O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
  • Tested applications:
    Bioassay

Specifications

About this item

GMP Reductase 1 (GMPR) is a member of the IMPDH/GMPR family. GMPR exists as a homotetramer and catalyses the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. GMP reductase gene expression may be regulated by MITF. At least two different alleles are known.

Fusion-Tag: C-6 His tag

This recombinant protein can be used for biological assays. For research use only.