Endoproteinase Lys-C protease is a highly purified native endoproteinase validated for maximum activity and stability in proteomic applications.

• Can be used in tandem with trypsin to decrease tryptic missed cleavages thus enhancing digestion
• Better protein characterisation results from overlapping peptides with complementary chromatographic, ionisation and fragmentation properties thereby increasing sequence coverage
• Effective enzyme activity under highly denaturing conditions
• C-terminal lysine cleavage specificity of 90% for a complex protein sample
• Stable since it is provided in a lyophilised format

Applications include improved sequence coverage of protein digests, de novo sequencing, epigenetic studies and in-gel and in-solution digestion of proteins.