Specifications
- Antibody type:Primary
- Antigen name:ANT1+ANT2+ANT3+ANT4
- Antigen symbol:ANT1+ANT2+ANT3+ANT4
- Clonality:Polyclonal
- Conjugation:Unconjugated
- Host:Rabbit
- ImmunoChemistry:Yes
- Isotype:IgG
- Reactivity:Human,Rat,Mouse
- Western blot:Yes
- Environmentally Preferable:
- Form:liquid
- Antigen synonyms:ATP carrier protein 3|ADP/ATP translocase 3|ADT1_HUMAN|ADP/ATP translocase 2|ANT 2|ADP/ATP translocase 4|ADP/ATP translocase 1|ADP ATP carrier protein heart/skeletal muscle isoform T4|ADT2_HUMAN|ATP carrier protein 4|ANT 4|ATP carrier protein 1|ANT 1|ADP ATP carrier protein heart/skeletal muscle isoform T3|ANT|ATP carrier protein 2|ANT3|ADT4_HUMAN|ADP ATP carrier protein heart/skeletal muscle isoform T1|ANT4.|ADT3_HUMAN|ANT1|ADP ATP carrier protein heart/skeletal muscle isoform T2
- Storage buffer:Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0,09% sodium azide. Store at -20°C for 12 months.
- Concentration:1 ug/ul
- Shipping temperature:4 °C
- Purification:Purified by Protein A.
- Size:100 μg
- Pk:100 µl
Specifications
About this item
Adenine nucleotide translocator (ANT) and the voltage-dependent anion-selective channel proteins 1 and 2 (VDAC1 and VDAC2) are components of the permeability transition pore complex (PTPC) of the mitochondrial inner and outer membranes, respectively. Formation of PTPCs, the subsequent dissipation of mitochondrial inner membrane potential and release of cytochrome c through the outer mitochondrial membrane are critical events in the early stages of apoptosis. Bax, a proapoptotic protein, has been shown to act upon ANT to induce the dissipation of mitochondrial inner membrane potential. ANT1 has a role in the maintenance of mitochondrial DNA by catalyzing the exchange of ADP and ATP across the mitochondrial inner membrane.
WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
Type: Primary
Antigen: ANT1+ANT2+ANT3+ANT4
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat