Specifications
- Antibody type:Primary
- Antigen name:Rap Guanine Nucleotide Exchange Factor 2
- Antigen symbol:RAGEF2
- Clonality:Polyclonal
- Conjugation:Unconjugated
- Host:Rabbit
- ImmunoChemistry:Yes
- Isotype:IgG
- Reactivity:Human,Rat,Mouse
- Western blot:Yes
- Environmentally Preferable:
- Form:liquid
- Antigen synonyms:PDZ domain-containing guanine nucleotide exchange factor 2|PDZ GEF 2|PDZ domain containing guanine nucleotide exchange factor 2|PDZ-GEF2|PDZGEF2|Rap guanine nucleotide exchange factor 6|RA GEF 2|RAGEF 2|PDZ domain containing guanine nucleotide exchange factor I|RA GEF2|RPGF6_HUMAN.|KIA001LB|PDZ domain containing guanine nucleotide exchange factor GEF 2|Rap guanine nucleotide exchange factor GEF 6|RA-GEF-2|DKFZp686I15116|Rap guanine nucleotide exchange factor 2|RAPGEF6|DKFZp667N084|PDZ GEF2|PDZGEF 2
- Storage buffer:Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0,09% sodium azide. Store at -20°C for 12 months.
- Concentration:1 ug/ul
- Shipping temperature:4 °C
- Purification:Purified by Protein A.
- Size:100 μg
- Pk:100 µl
Specifications
About this item
RAPGEF6 is a guanine nucleotide exchange factor (GEF) that is expressed in a variety of tissues. Localizing to the cytoplasm and translocated to the plasma membrane upon ligand binding, RAPGEF6 contains an N-terminal Ras-GEF domain, a cyclic nucleotide monophosphate-binding domain, a PDZ (PSD-95/DlgA/ZO-1) domain, a Ras-associating (RA) domain and a Ras exchanger motif. RAPGEF6 is closely related to RAPGEF2 and both proteins exhibit GEF activity specific towards Rap 1 and Rap 2. In addition, RAPGEF6 is capable of binding to M-Ras via its RA domain. Due to alternative splicing events, two additional isoforms exist for RAPGEF6, namely PDZ-GEF2A and PDZ-GEF2B.
WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
Type: Primary
Antigen: RAGEF2
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat