Anti-TTC21B Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog # BOSSBS-12069R-A750

Supplier: Bioss

Catalog # BOSSBS-12069R-A750

Supplier: Bioss

Specifications

Antibody type:
Primary
Antigen name:
TTC21B
Clonality:
Polyclonal
Conjugation:
Alexa Fluor® 750
Host:
Rabbit
ImmunoChemistry:
Yes
ImmunoFluorescence:
Yes
Isotype:
IgG
Reactivity:
Rat
Environmentally Preferable:
Epitope:
1221-1316/1316
Form:
Liquid
Gene ID:
79809
Antigen synonyms:
ATD4|NPHP12|Ttc21b|Tetratricopeptide repeat protein 21B|THM1|TPR repeat protein 21B|JBTS11|TT21B_HUMAN|Putative protein product of Nbla10696|Nbla10696
Modification:
Unmodified
Storage buffer:
Aqueous buffered solution containing 0,01 M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol
Molecular weight:
150 kDa
Storage temperature:
Store at −20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Concentration:
1 µg/µl
Shipping temperature:
4 °C
Immunogen:
KLH conjugated synthetic peptide derived from human TTC21B
Tested applications:
ICC
Purification:
Purified by Protein A
Pack type:
Vial
Pk:
100 µl

Specifications

About this item

The tetratricopeptide repeat (TPR) motif is a degenerate, 34 amino acid sequence found in many proteins and acts to mediate protein-protein interactions in various pathways. At the sequence level, there can be up to 16 tandem TPR repeats, each of which has a helix-turn-helix shape that stacks on other TPR repeats to achieve ligand binding specificity. TTC21B (tetratricopeptide repeat domain 21B), also known as THM1, is a 1316 amino acid protein that contains 19 TPR repeats and belongs to the TTC21 family. Localizing to cytoplasm and cytoskeleton, TTC21B exists as two alternatively spliced isoforms and is thought to negatively regulate Shh signal transduction. TTC21B may also be involved in retrograde intraflagellar transport in cilia, and is encoded by a gene that maps to human chromosome 2q24.3.

Type: Primary
Antigen: TTC21B
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 750
Public Immunogen Range: 1221-1316/1316
Host: Rabbit
Isotype: IgG
Reactivity: Rat