Anti-TFCP2C Rabbit Polyclonal Antibody (Alexa Fluor® 680)

BOSSBS-9852R-A680

Anti-TFCP2C Rabbit Polyclonal Antibody (Alexa Fluor® 680)

BOSSBS-9852R-A680

Antibody type:
Primary
Antigen name:
TFCP2C
Clonality:
Polyclonal
Conjugation:
Alexa Fluor® 680
Host:
Rabbit
ImmunoChemistry:
Yes
ImmunoFluorescence:
Yes
Isotype:
IgG
Reactivity:
Human,
Rat,
Mouse
Western blot:
Yes
Environmentally Preferable:
Epitope:
201-300/502
Form:
Liquid
Gene ID:
7024
Antigen synonyms:
LSF|Alpha globin transcription factor CP2|SAA3 enhancer factor|CP2|LBP 1C|TFCP2_HUMAN|SEF|LBP1C|Transcription factor CP2|TFCP2|TFCP2C|Transcription factor LSF
Modification:
Unmodified
Storage buffer:
Aqueous buffered solution containing 0,01 M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol
Storage temperature:
Store at −20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Concentration:
1 µg/µl
Shipping temperature:
4 °C
Immunogen:
KLH conjugated synthetic peptide derived from human TFCP2C
Purification:
Purified by Protein A
Pack type:
Vial
Pk:
100 µl

CP2 family gene products are reported to be involved in a-globin gene expression. Mouse CP2c (also known as a-CP2/CP2/LSF/UBP-1) is a homologue of human LBP-1c with 96% amino acid sequence identity. CP2c was initially identified as an activator of the mouse a-globin gene, which binds to the consensus DNA-binding sequence CNRG-N6-CNR(G/C) within a promoter element overlapping the CCAAT box. The transcriptional activity of CP2c was increased during induced differentiation of MEL cells and associated globin gene transcription. CP2c is also likely to be involved in regulation of non-globin erythroid-specific genes. It was reported that congenital erythropoietic porphyria was caused by the mutations in GATA-1 and CP2c binding sites within the promoter of the uroporphyrinogen III synthase gene, the fourth enzyme in the heme biosynthetic pathway.

Type: Primary
Antigen: TFCP2C
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 680
Public Immunogen Range: 201-300/502
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat