- Antibody type:Primary
- Antigen name:WBSCR14
- Clonality:Polyclonal
- Conjugation:Alexa Fluor® 750
- Host:Rabbit
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Isotype:IgG
- Reactivity:Rat
- Environmentally Preferable:
- Epitope:81-180/852
- Form:Liquid
- Gene ID:51085
- Antigen synonyms:Williams Beuren syndrome chromosome region 14|Williams Beuren syndrome chromosome region 14 protein|WS basic helix loop helix leucine zipper protein|WBSCR14|WBSCR 14|MLXPL_HUMAN|ChREBP|MLX interacting protein like|WS bHLH|bHLHd14|MIO|Carbohydrate responsive element binding protein|MONDOB|MLXIPL|Mlx interactor
- Modification:Unmodified
- Storage buffer:Aqueous buffered solution containing 0,01 M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol
- Molecular weight:93 kDa
- Storage temperature:Store at −20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Concentration:1 µg/µl
- Shipping temperature:4 °C
- Immunogen:KLH conjugated synthetic peptide derived from human WBSCR14/ChREBP
- Tested applications:ICC
- Purification:Purified by Protein A
- Pack type:Vial
- Pk:100 µl
ChREBP (Carbohydrate responsive element binding protein) is a transcription factor playing a critical role in the nutrient and hormonal regulation of genes encoding enzymes of glucose metabolism and lipogenesis pathways. It contains several domains including a nuclear localization signal (NLS) near the N-terminus, polyproline domains, a basic helix-loop-helix leucine zipper (b/HLH/Zip) and a leucine zipper like (zip-like) domain.ChREBP is ubiquitously detected in various tissues, with highest expression in liver, kidney and white and brown adipose tissue. Under basal conditions ChREBP is localized in the cytosol, translocating into the nucleus upon high glucose stimulation following its dephosphorylation of serine 196.
Type: Primary
Antigen: WBSCR14
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 750
Public Immunogen Range: 81-180/852
Host: Rabbit
Isotype: IgG
Reactivity: Rat