Anti-DKK1 Rabbit Polyclonal Antibody (Alexa Fluor® 680)
Catalog # BOSSBS-2162R-A680
Supplier: Bioss
Specifications
- Antibody type:Primary
- Antigen name:DKK1
- Clonality:Polyclonal
- Conjugation:Alexa Fluor® 680
- Host:Rabbit
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Isotype:IgG
- Reactivity:Human,Dog
- Western blot:Yes
- Environmentally Preferable:
- Epitope:201-266/266
- Form:Liquid
- Gene ID:22943
- Antigen synonyms:UNQ492/PRO18|SK|hDkk-1|DKK1|Dickkopf-related protein 1|Dickkopf-1|DKK-1
- Modification:Unmodified
- Storage buffer:Aqueous buffered solution containing 0,01 M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol
- Molecular weight:29 kDa
- Storage temperature:Store at –20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Concentration:1 µg/µl
- Shipping temperature:4 °C
- Immunogen:KLH conjugated synthetic peptide derived from human DKK1
- Tested applications:ICC
- Purification:Purified by Protein A
- Pack type:Vial
- Pk:100 µl
Specifications
About this item
Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalisation of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease.
Type: Primary
Antigen: DKK1
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 680
Public Immunogen Range: 201-266/266
Host: Rabbit
Isotype: IgG
Reactivity: Human, Dog