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Anti-DKK1 Rabbit Polyclonal Antibody (Alexa Fluor® 680)
Anti-DKK1 Rabbit Polyclonal Antibody (Alexa Fluor® 680)
Catalog # BOSSBS-2162R-A680
Supplier:  Bioss
Anti-DKK1 Rabbit Polyclonal Antibody (Alexa Fluor® 680)
Catalog # BOSSBS-2162R-A680
Supplier:  Bioss

Specifications

  • Antibody type:
    Primary
  • Antigen name:
    DKK1
  • Clonality:
    Polyclonal
  • Conjugation:
    Alexa Fluor® 680
  • Host:
    Rabbit
  • ImmunoChemistry:
    Yes
  • ImmunoFluorescence:
    Yes
  • Isotype:
    IgG
  • Reactivity:
    Human,
    Dog
  • Western blot:
    Yes
  • Environmentally Preferable:
  • Epitope:
    201-266/266
  • Form:
    Liquid
  • Gene ID:
    22943
  • Antigen synonyms:
    UNQ492/PRO18|SK|hDkk-1|DKK1|Dickkopf-related protein 1|Dickkopf-1|DKK-1
  • Modification:
    Unmodified
  • Storage buffer:
    Aqueous buffered solution containing 0,01 M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol
  • Molecular weight:
    29 kDa
  • Storage temperature:
    Store at –20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
  • Concentration:
    1 µg/µl
  • Shipping temperature:
    4 °C
  • Immunogen:
    KLH conjugated synthetic peptide derived from human DKK1
  • Tested applications:
    ICC
  • Purification:
    Purified by Protein A
  • Pack type:
    Vial
  • Pk:
    100 µl

Specifications

About this item

Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalisation of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease.

Type: Primary
Antigen: DKK1
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 680
Public Immunogen Range: 201-266/266
Host: Rabbit
Isotype: IgG
Reactivity: Human, Dog