Anti-ATG4B Rabbit Polyclonal Antibody
Catalog # BOSSBS-1384R
Supplier: Bioss
Specifications
- Antibody type:Primary
- Antigen name:ATG4B
- Clonality:Polyclonal
- Conjugation:Unconjugated
- ELISA:Yes
- Host:Rabbit
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Isotype:IgG
- Reactivity:Human,Rat,Mouse
- Environmentally Preferable:
- Epitope:85-200/392
- Form:Liquid
- Gene ID:23192
- Antigen synonyms:Cysteine protease ATG4B|Autophagy-related cysteine endopeptidase 1|hAPG4B|Autophagy-related protein 4 homolog B|AUT-like 1 cysteine endopeptidase|Autophagin-1|KIAA0943|APG4B|AUTL1|ATG4B
- Modification:Unmodified
- Storage buffer:0,01 M TBS(pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol
- Molecular weight:44 kDa
- Storage temperature:Shipped at 4 °C. Store at –20 °C for one year. Avoid repeated freeze/thaw cycles.
- Concentration:1 µg/µl
- Shipping temperature:4 °C
- Immunogen:KLH conjugated synthetic peptide derived from human ATG4B
- Tested applications:ICC
- Purification:Purified by Protein A
- Pack type:Vial
- Pk:100 µl
Specifications
About this item
Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3, GABARAPL1, GABARAPL2 and GABARAP, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms.
Type: Primary
Antigen: ATG4B
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Public Immunogen Range: 85-200/392
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat