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Anti-ATG4B Rabbit Polyclonal Antibody
Anti-ATG4B Rabbit Polyclonal Antibody
Catalog # BOSSBS-1384R
Supplier:  Bioss
Anti-ATG4B Rabbit Polyclonal Antibody
Catalog # BOSSBS-1384R
Supplier:  Bioss

Specifications

  • Antibody type:
    Primary
  • Antigen name:
    ATG4B
  • Clonality:
    Polyclonal
  • Conjugation:
    Unconjugated
  • ELISA:
    Yes
  • Host:
    Rabbit
  • ImmunoChemistry:
    Yes
  • ImmunoFluorescence:
    Yes
  • Isotype:
    IgG
  • Reactivity:
    Human,
    Rat,
    Mouse
  • Environmentally Preferable:
  • Epitope:
    85-200/392
  • Form:
    Liquid
  • Gene ID:
    23192
  • Antigen synonyms:
    Cysteine protease ATG4B|Autophagy-related cysteine endopeptidase 1|hAPG4B|Autophagy-related protein 4 homolog B|AUT-like 1 cysteine endopeptidase|Autophagin-1|KIAA0943|APG4B|AUTL1|ATG4B
  • Modification:
    Unmodified
  • Storage buffer:
    0,01 M TBS(pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol
  • Molecular weight:
    44 kDa
  • Storage temperature:
    Shipped at 4 °C. Store at –20 °C for one year. Avoid repeated freeze/thaw cycles.
  • Concentration:
    1 µg/µl
  • Shipping temperature:
    4 °C
  • Immunogen:
    KLH conjugated synthetic peptide derived from human ATG4B
  • Tested applications:
    ICC
  • Purification:
    Purified by Protein A
  • Pack type:
    Vial
  • Pk:
    100 µl

Specifications

About this item

Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3, GABARAPL1, GABARAPL2 and GABARAP, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms.

Type: Primary
Antigen: ATG4B
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Public Immunogen Range: 85-200/392
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat