Isolate or deplete highly purified HLA-DR+ cells from human PBMCs or leukapheresis samples by immunomagnetic selection.

• Fast and easy-to-use
• Up to 98% purity
• No columns required

Efficiently isolate or deplete HLA-DR+ cells from fresh or previously frozen human peripheral blood mononuclear cells (PBMCs) or leukapheresis samples in as little as 25 minutes; and immediately use the desired cells in downstream applications such as flow cytometry, culture, or DNA/RNA extraction.

Use the EasySep™ Human HLA-DR Positive Selection and Depletion Kit to label HLA-DR+ cells with antibodies and magnetic particles. The cells are then subsequently separated using an EasySep™ magnet—without the use of columns. Labeled cells remain in the tube while unlabeled cells are poured off. Depending on your research needs, either fraction may be used downstream.

This kit targets HLA-DR, a human major histocompatibility complex (MHC) class II receptor expressed on the cell surface of antigen-presenting cells (APCs), including dendritic cells, B cells, monocytes, macrophages, and activated T cells.