Human recombinant Fructose-1,6-Bisphosphatase 1 (from cells)
PRSI91-948
:
- Pk:50 µG
- Enzyme type:Recombinant
- Source:Cells
- Species:Human
- Environmentally Preferable:
- Tag sequence:C-6 His tag
- Storage conditions:Store at −20 °C, stable for 6 months after receipt. Please minimize freeze−thaw cycles.
- Enzyme name:Fructose-1,6-Bisphosphatase 1
- Purity:>95% as determined by reducing SDS-PAGE
- Molecular weight:37.8 kD
- Sequence:Ala2-Gln338
- Formulation:Supplied as a 0.2 µm filtered solution of 20 mM TrisHCl,200 mM NaCl,1 mM DTT, 10% Glycerol, pH 8.0. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH₂O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
- Tested applications:Bioassay
Fructose-1,6-bisphosphatase 1(FBP1) is a homotetramer protein and belongs to the FBPase class 1 family. It involves in carbohydrate biosynthesis; gluconeogenesis pathway. FBP1 is a gluconeogenesis regulatory protein which catalyses the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate and inorganic phosphate. FBP1 deficiency is associated with hypoglycemia and metabolic acidosis. FBP1 regulates mouse endogenous glucose production. FBP1 coupled with phosphofructokinase (PFK) takes part in the metabolism of pancreatic islet cells.
Fusion-Tag: C-6 His tag
This recombinant protein can be used for biological assays. For research use only.