Specifications
- Pk:50 µG
- Protein/peptide type:Recombinant
- Source:
- Species:Mouse
- Environmentally Preferable:
- Tag sequence:C-6 His tag
- Storage conditions:Lyophilized protein should be stored at −20 °C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7 °C for 2-7 days. Aliquots of reconstituted samples are stable at −20 °C for 3 months.
- Protein synonyms:apM-1|Adipocyte|Gelatin-Binding Protein|Adipose Most Abundant Gene Transcript 1 Protein|Adiponectin|ADIPOQ|30 kDa Adipocyte Complement-Related Protein|ACRP30|Adipocyte complement-related 30 kDa protein|C1q and Collagen Domain-Containing Protein
- Protein/peptide name:Adiponectin
- Purity:> 95% as determined by reducing SDS-PAGE
- Molecular weight:27.6 kD
- Sequence:Glu18-Asn247
- Formulation:Lyophilized from a 0.2 um filtered solution of 20mM PB,150mM NaCl,pH7.4. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the Lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
- Tested applications:Bioassay
Specifications
About this item
Adiponectin is a secreted protein. It is Synthesised exclusively by adipocytes and secreted into plasma. Adiponectin is an important adipokine that is involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Adiponectin Stimulates AMPK phosphorylation and activates in the liver and the skeletal muscle, enhancing glucose utilisation and fatty-acid combustion. Adiponectin also antagonises TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. It inhibits endothelial NF-kappa-B signalling through a cAMP-dependent pathway. Adiponectin may play a role in cell growth, angiogenesis and tissue remodelling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex: LMW, MMW or HMW.
Fusion-Tag: C-6 His tag
This recombinant protein can be used for biological assays. For research use only.