Specifications
- Antigen name:Thyroid Hormone Receptor, Beta
- Antigen symbol:THRB
- Clonality:Monoclonal
- Conjugation:Unconjugated
- Host:Mouse
- Isotype:IgG1
- Reactivity:Human
- Western blot:Yes
- Environmentally Preferable:
- Form:Liquid
- Antigen synonyms:GRTH|ERBA-BETA|THRB2|NR1A2|ERBA2|MGC126109|thyroid hormone receptor|avian)|oncogene ERBA2|THRB1|beta|MGC126110|THR1|thyroid hormone receptor beta 1|avian erythroblastic leukemia viral (v-erb-a) oncogene homolog 2|generalized resistance to thyroid hormone|beta (erythroblastic leukemia viral (v-erb-a) oncogene homolog 2|Thyroid hormone receptor
- Immunogen:Peptide corresponding to amino acid residues from the N-terminal region of human thyroid hormone receptor, b-isotype.
- Size:100 µl
- Pk:100 µl
Specifications
About this item
Thyroid hormones are essential for development of the central nervous system and deficits in these hormones during development affects such cognitive functions as learning and memory (Ambrogini et al., 2005; Chan and Kilby, 2000). Thyroid hormones exert their physiological role mainly through binding to specific nuclear receptors including the predominant isoforms of thyroid hormone receptors TRalpha1, TRalpha2, TRbeta1 and TRbeta2. TRalpha1, TRbeta1 and TRbeta2 bind T3 with high affinity and also bind to thyroid hormone response elements (TREs) on chromatin to regulate the transcriptional processes in several target tissues, including adult rat brain (Constantinou et al., 2005).
The antibody has been directly tested for reactivity in Western blots with human tissue.
Protein G purified
100 uL in 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 ug per mL BSA and 50% glycerol.
Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
Type:
Antigen: THRB
Clonality: Monoclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype: IgG1
Reactivity: Human