- Antigen name:Transmembrane 4 L Six Family Member 1
- Antigen symbol:TM4SF1
- Clonality:Polyclonal
- Conjugation:Unconjugated
- ELISA:Yes
- Host:Rabbit
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Isotype:IgG
- Reactivity:Human,Rat,Mouse
- Western blot:Yes
- Environmentally Preferable:
- Antigen synonyms:Membrane component chromosome 3 surface marker 1|T4S1_HUMAN|Transmembrane 4 L6 family member 1|TAAL6,Tm4sf1|M3S1|Tumor-associated antigen L6.
- Storage buffer:PBS containing 0.02% sodium azide
- Immunogen:TM4SF1 antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human TM4SF1.
- Tested applications:E, WB, IHC, IF
- Purification:Affinity chromatography purified via peptide column
- Size:100 µg
- Pk:100 µG
TM4SF1 Antibody: TM4SF1 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains and mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. TM4SF1 is a cell surface antigen and is highly expressed in the vascular endothelium of several human cancers. Knockdown experiments of TM4SF1 prevented filopodia formation, inhibited cell mobility, blocked cytokinesis, and inhibited maturation of VEGF-A-induced angiogenesis, suggesting that TM4SF1 may be an attractive target for anti-angiogenesis therapy.
Type:
Antigen: TM4SF1
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat