Specifications
- Antigen name:Raf-1 Proto-Oncogene, Serine/Threonine Kinase
- Antigen symbol:C-RAF
- Clonality:Polyclonal
- Conjugation:Unconjugated
- ELISA:Yes
- Host:Chicken
- Isotype:IgY
- Reactivity:Human,Rat,Mouse
- Western blot:Yes
- Environmentally Preferable:
- Antigen synonyms:C-Raf|Raf-1|Raf proto-oncogene serine/threonine-protein kinase|RAF1|CRAF|RAF-1|RAF proto-oncogene serine/threonine-protein kinase|EC 2.7.11.1|Similar to murine leukemia viral (V-raf-1) oncogene homolog 1|C-RAF|Protein kinase raf 1|kinase Raf1
- Storage buffer:PBS containing 0.02% sodium azide
- Immunogen:C-raf antibody was raised against an 19 amino acid synthetic peptide near the amino terminus of human C-raf.
- Tested applications:E, WB
- Purification:Affinity chromatography purified via peptide column
- Size:100 µg
- Pk:100 µG
Specifications
About this item
C-raf Antibody: C-raf is the cellular homolog of viral raf gene (v-raf) and encodes a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases. Once activated, C-raf phosphorylates and activates the protein kinases MEK1 and MEK2, which in turn phosphorylate and activate the serine/threonine specific protein kinases, ERK1 and ERK2. These activated ERKs are pleiotropic effectors of cell physiology and play an important role in the control of gene expression involved in the cell division cycle, apoptosis, cell differentiation and cell migration. Mutations in this gene are associated with Noonan syndrome 5 and LEOPARD syndrome 2.
Type:
Antigen: C-RAF
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Chicken
Isotype:
Reactivity: