Anti-TNFR1 Rabbit Polyclonal Antibody (Alexa Fluor® 350)
Catalog # BOSSBS-2941R-A350
Supplier: Bioss
Specifications
- Antibody type:Primary
- Antigen name:Tumer Necrosis Factor Receptor 1
- Antigen symbol:TNFR1
- Clonality:Polyclonal
- Conjugation:Alexa Fluor® 350
- Host:Rabbit
- ImmunoChemistry:Yes
- Isotype:IgG
- Reactivity:Human,Rat,Mouse
- Environmentally Preferable:
- Cross adsorption:No
- Form:liquid
- Gene ID:7132
- Antigen synonyms:TNFRSF1A|Tumor necrosis factor receptor superfamily member 1A [Precursor]|TNFR-I|p55|CD120a antigen|TNFAR|p60|TNF-R1|TNFR1|TNF-RI
- Storage buffer:Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
- Storage temperature:Store at 4°C for 12 months
- Concentration:1 μg/μl
- Shipping temperature:4°C
- Immunogen:22-72/455
- Purification:Purified by Protein A
- Pk:100 µl
Specifications
About this item
Receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Contributes to the induction of non-cytocidal TNF effects including anti-viral state and activation of the acid sphingomyelinase.
Recommended Dilutions: IF(IHC-P): 1:50-200
Type: Primary
Antigen: TNFR1
Clonality: Polyclonal
Clone:
Conjugation: Alexa Fluor® 350
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat