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Anti-TNFR1 Rabbit Polyclonal Antibody (Alexa Fluor® 350)
Anti-TNFR1 Rabbit Polyclonal Antibody (Alexa Fluor® 350)
Catalog # BOSSBS-2941R-A350
Supplier:  Bioss
Anti-TNFR1 Rabbit Polyclonal Antibody (Alexa Fluor® 350)
Catalog # BOSSBS-2941R-A350
Supplier:  Bioss

Specifications

  • Antibody type:
    Primary
  • Antigen name:
    Tumer Necrosis Factor Receptor 1
  • Antigen symbol:
    TNFR1
  • Clonality:
    Polyclonal
  • Conjugation:
    Alexa Fluor® 350
  • Host:
    Rabbit
  • ImmunoChemistry:
    Yes
  • Isotype:
    IgG
  • Reactivity:
    Human,
    Rat,
    Mouse
  • Environmentally Preferable:
  • Cross adsorption:
    No
  • Form:
    liquid
  • Gene ID:
    7132
  • Antigen synonyms:
    TNFRSF1A|Tumor necrosis factor receptor superfamily member 1A [Precursor]|TNFR-I|p55|CD120a antigen|TNFAR|p60|TNF-R1|TNFR1|TNF-RI
  • Storage buffer:
    Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
  • Storage temperature:
    Store at 4°C for 12 months
  • Concentration:
    1 μg/μl
  • Shipping temperature:
    4°C
  • Immunogen:
    22-72/455
  • Purification:
    Purified by Protein A
  • Pk:
    100 µl

Specifications

About this item

Receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Contributes to the induction of non-cytocidal TNF effects including anti-viral state and activation of the acid sphingomyelinase.

Recommended Dilutions: IF(IHC-P): 1:50-200

Type: Primary
Antigen: TNFR1
Clonality: Polyclonal
Clone:
Conjugation: Alexa Fluor® 350
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat