About this item
Anti-globulin reagent (Coombs' serum) is prepared by immunizing rabbits with canine IgG, IgM and C3 purified from normal serum. The resulting whole antiserum is heat treated to inactivate complement and is adsorbed with normal pooled canine erythrocytes to remove nonspecific agglutinins.
- Can be reconstitute with deionized water
- Suitable for Autoimmune hemolytic anemia screening
- One ml of reconstituted material is sufficient for 10 tests by the tube method or 50 when using the microtiter plate method
It is widely used to detect the presence of antibody in the diagnosis of autoimmune hemolytic anemia. Antibody alone or in the presence of complement injures the cell membrane permitting leakage of RBC material, allowing recognition by the reticuloendothelial cells, thereby leading to phagocytosis and destruction of RBC's.
Type: Primary
Antigen: Globulin (Coombs' test)
Clonality: Polyclonal
Clone:
Conjugation:
Epitope:
Host: Rabbit
Isotype:
Reactivity: Dog
Specifications
- Catalog No:
- ICNA08646351
- ICNA08646352
- Antigen symbol:
- IgG, IgM, C3
- Antigen name:
- Globulin (Coombs' test)
- Antibody type:
- Primary
- Primary
- Clonality:
- Polyclonal
- Polyclonal
- Reactivity:
- Dog
- Dog
- Host:
- Rabbit
- Rabbit
- Isotype:
- IgG
- IgG
- ELISA:
- Yes
- ImmunoChemistry:
- Yes
- ImmunoPrecipitation:
- Yes
- ImmunoFluorescence:
- Yes
- Format:
- Antiserum
- Antiserum
- Form:
- Lyophilized
- Lyophilised
- Storage temperature:
- +2 °C to +8 °C
- +2 °C to +8 °C
- Shipping temperature:
- RT
- Tested applications:
- Autoimmune hemolytic anemia screening
- Autoimmune hemolytic anemia screening
Specifications
Supplier: HEATHROW
Supplier: VWR Chemicals
Supplier: VWR Collection
Supplier: VWR Chemicals
Supplier: VWR Collection
Supplier: Merck
Supplier: VWR Chemicals
Supplier: VWR Chemicals
Supplier: VWR Collection
Supplier: VWR Collection
Supplier: VWR Collection
Supplier: KIMBERLY CLARK