Thermo Scientific™ GeneRuler™ and O'GeneRuler™ DNA ladders are mixtures of chromatography-purified individual DNA fragments. The GeneRuler™ line includes the most popular ladders, such as the 100 bp and 1 kb DNA Ladder. GeneRuler™ DNA ladders are available in two formats: Conventional (provided in TE buffer) and a ready-to-use format (premixed with 6X DNA Loading Dye which contains bromophenol blue and xylene cyanol FF). O'GeneRuler™ DNA ladders are another ready-to-use version of GeneRuler™ DNA ladders that are premixed with 6X Orange DNA Loading Dye.

• Universal ladders for DNA sizing and quantification—cover broad range of DNA molecular weights and provide DNA amount per band
• Sharp bands, bright reference bands
• Supplied with loading dye for sample DNA
• Ready-to-use ladders are stable for 6 months at room temperature

GeneRuler™ 1 kb, 100 bp, and 50 bp DNA ladders are recommended for sizing and approximate quantification of a wide range of double-stranded DNA on agarose gels. GeneRuler™ DNA low range and high range ladders are best for sizing and approximate quantification of double-stranded DNA at low and high DNA size ranges.

O’GeneRuler™ DNA ladders are premixed with 6X Orange DNA Loading Dye, which contains xylene cyanol FF and orange G. In a 1% agarose gel orange G dye migrates at 50 bp. Therefore, O’GeneRuler™ DNA ladders are ideal to use when visualisation of small DNA fragments is important.