Anti-RAE1 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Catalog # BOSSBS-3791R-A555

Supplier: Bioss

Catalog # BOSSBS-3791R-A555

Supplier: Bioss

Specifications

Antibody type:
Primary
Antigen name:
Ribonucleic Acid Export 1
Antigen symbol:
RAE1
Clonality:
Polyclonal
Conjugation:
Alexa Fluor® 555
Host:
Rabbit
ImmunoChemistry:
Yes
Isotype:
IgG
Reactivity:
Human,
Rat,
Mouse
Environmentally Preferable:
Cross adsorption:
No
Form:
liquid
Gene ID:
8480
Antigen synonyms:
mRNA-associated protein MRNP 41|MIG14|MGC126076|OTTHUMP00000166110|RP4-800J21.2|mRNA-binding protein|dJ481F12.3|mRNA export protein|migration-inducing gene 14|MGC126077|MRNP41|HGNC:9828|RAE1|Mnrp41|S.pombe) homolog|homolog of yeast Rae1 (Bharathi) mRNA-associated protein of 41 kDa (Kraemer)|MGC117333|FLJ30608|41-kD|dJ800J21.1|RAE1 RNA export 1 homolog (S. pombe) |RAE1 (RNA export 1
Storage buffer:
Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
Storage temperature:
Store at 4°C for 12 months
Concentration:
1 μg/μl
Shipping temperature:
4°C
Purification:
Purified by Protein A
Pk:
100 µl

Specifications

About this item

Mutations in Rae1 and Gle2(Saccharomyces cerevisae homolog) genes have been shown to result in accumulation of poly(A)-containing mRNA in the nucleus, suggesting that the encoded proteins are involved in RNA export. It contains four WD40 motifs, and has been shown to localize to distinct foci in the nucleoplasm, to the nuclear rim, and to meshwork-like structures throughout the cytoplasm. This gene is thought to be involved in nucleocytoplasmic transport, and in directly or indirectly attaching cytoplasmic mRNPs to the cytoskeleton. Depletion of Rae1 from extracts or cells severely inhibits mitotic spindle assembly. Alternatively spliced transcript variants encoding the same protein have been found for this gene.

Recommended Dilutions: IF(IHC-P): 1:50-200

Type: Primary
Antigen: RAE1
Clonality: Polyclonal
Clone:
Conjugation: Alexa Fluor® 555
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat