Anti-Glyt1/SLC6A9 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog # BOSSBS-11604R-A680

Supplier: Bioss

Catalog # BOSSBS-11604R-A680

Supplier: Bioss

Specifications

Antibody type:
Primary
Antigen name:
Glyt1/SLC6A9
Clonality:
Polyclonal
Conjugation:
Alexa Fluor® 680
Host:
Rabbit
ImmunoChemistry:
Yes
ImmunoFluorescence:
Yes
Isotype:
IgG
Reactivity:
Human,
Rat,
Mouse
Western blot:
Yes
Environmentally Preferable:
Epitope:
209-285/706
Form:
Liquid
Gene ID:
6536
Antigen synonyms:
GlyT-1 antibodyGlyT1|Glyt 1|SC6A9_HUMAN|Sodium- and chloride-dependent glycine transporter 1|glycine transporter 1|sodium and chloride dependent glycine transporter 1|Solute carrier family 6 member 9|SLC6A9
Modification:
Unmodified
Storage buffer:
Aqueous buffered solution containing 0,01 M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol
Molecular weight:
78 kDa
Storage temperature:
Store at −20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Concentration:
1 µg/µl
Shipping temperature:
4 °C
Immunogen:
KLH conjugated synthetic peptide derived from human Glyt1/SLC6A9
Tested applications:
ICC
Purification:
Purified by Protein A
Pack type:
Vial
Pk:
100 µl

Specifications

About this item

Na⁺/Cl⁻ dependent neurotransmitter transporters are a superfamily of transmembrane proteins that contain 12 membrane spanning regions. Specifically, the highly hydrophobic Na⁺/Cl⁻ dependent glycine transporters (GlyT) are crucial for the termination of neurotransmission at glycinergic synapses. Two different GlyT genes encode GlyT2 and GlyT1, which exists as two isoforms produced by alternative splicing of the same gene located on human chromosome 1p31.3. The GlyT1 gene may be an early marker of neural development and encodes glia-specific transporter proteins. Although GlyT1 and GlyT2 are both expressed in the brain and spinal cord, each shows a unique pattern of expression. GlyT1 is found only in the white matter of the CNS, whereas GlyT2 is found in the gray matter of the CNS as well as in macrophages and mast cells in peripheral tissues. The anatomic distribution of GlyT2 mRNA suggests that glycine may act as a supraspinal neurotransmitter and may function as a chemical messenger outside the CNS.

Type: Primary
Antigen: Glyt1/SLC6A9
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 680
Public Immunogen Range: 209-285/706
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat