Anti-CADPS2 Rabbit Polyclonal Antibody

Catalog # BOSSBS-11500R

Supplier: Bioss

Catalog # BOSSBS-11500R

Supplier: Bioss

Specifications

Antibody type:
Primary
Antigen name:
Ca++-dependent Secretion Activator 2
Antigen symbol:
CADPS2
Clonality:
Polyclonal
Conjugation:
Unconjugated
Host:
Rabbit
ImmunoChemistry:
Yes
Isotype:
IgG
Reactivity:
Human,
Rat,
Mouse
Western blot:
Yes
Environmentally Preferable:
Form:
liquid
Antigen synonyms:
KIAA1591|CAPS2|Calcium-dependent secretion activator 2|CAPS-2|Calcium-dependent activator protein for secretion 2
Storage buffer:
Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0,09% sodium azide. Store at -20°C for 12 months.
Concentration:
1 ug/ul
Shipping temperature:
4 °C
Purification:
Purified by Protein A.
Size:
100 μg
Pk:
100 µl

Specifications

About this item

Calcium-dependent secretion activators (CAPS-1 and CAPS-2) are calcium-binding proteins that direct neurotransmitter and neuropeptide-filled vesicles to the cell membrane for secretory granule exocytosis. Both CAPS-1 and CAPS-2 are expressed primarily in the brain where they regulate the secretion of various substances. The CAPS proteins contain a PH domain that is essential for regulation of exocytosis, as well as regulation of phospholipid binding. Through their regulation of neurotrophin release from granule cells, CAPS proteins help to regulate cell fate during neuronal development. CAPS-1 is thought to regulate catecholamine release from neuronal cells, while CAPS-2 is thought to regulate release of both brain-derived neurotrophic factor and neurotrophin-3 from granule cells. Defects in the genes encoding CAPS-1 and CAPS-2 are implicated in impaired cerebral development and autism.

WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)

Type: Primary
Antigen: CADPS2
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG1
Reactivity: Human, Mouse, Rat