Anti-TNFRSF10B Mouse Monoclonal Antibody [clone: HS201]
PRSI36-128
- Antikörper-Typ:Primär
- Antigen-Name:Tumor Necrosis Factor Receptor Superfamily Member 10B
- Antigen-Symbol:TNFRSF10B
- Klonalität:Monoklonal
- Klon:HS201
- Konjugation:Unconjugated
- Durchflusszytometrie:Yes
- Wirt:Mouse
- ImmunoChemie:Yes
- Immunpräzipitation:Yes
- Isotyp:IgG1
- Reaktivität:Human
- Environmentally Preferable:
- Form:Liquid
- Gen-ID:8795
- Antigen-Synonyme:Tumor necrosis factor receptor superfamily member 10B|TRAIL receptor 2|TRAILR2|TRAIL-R2|TRICK2|KILLER|Death receptor 5|ZTNFR9|TNFRSF10B|CD_antigen=CD262|TNF-related apoptosis-inducing ligand receptor 2|DR5
- Lagerungspuffer:In PBS containing 10% glycerol and 0.02% sodium azide.
- Lagertemperatur:Stable for at least 1 year after receipt when stored at -20˚C.
- Konzentration:1 mg/ml
- Transporttemperatur:-20°C
- Immunogen:Recombinant human TRAIL-R2 (DR5).
- Validierte Anwendungen:FACS, Func,
- Reinigung:>95% (SDS-PAGE)
- Größe:100 μg
- VE:100 µG
TRAIL-R2 is a receptor for the cytotoxic ligand TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappaB.
Type: Primary
Antigen: TNFRSF10B
Clonality: Monoclonal
Clone: HS201
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype: IgG1
Reactivity: Human