3D Organoid Technologies for Modeling Development and Disease
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This seminar will discuss the following topics:
- Organoid cultures for modeling development
- Extracellular matrices for growing organoids including Matrigel Matrix, Collagen I and Matrigel for Organoids
- iPSC derived intestinal organoids for high throughput screening using Matrigel matrix and spheroid microplates
- High throughput gene expression analysis of airway organoids
- Benefits of organoid cultures for disease modeling
Presented by
Chris Suarez, Ph.D., Field Application Scientist Manager
Dr. Chris Suarez is the Manager of the Field Application Scientist team at Corning Life Sciences. He received his Ph.D. in Medicinal Chemistry and Molecular Pharmacology from Purdue University working on viral production, cell line engineering and cancer biology. Dr. Suarez has held positions in academia focusing on translational research to overcome mechanisms of therapeutic resistance in breast and prostate cancer using 3D tumor organoid models. Dr. Suarez works extensively with process development groups, optimizing production capabilities and cellular scale-up conditions from viral production to cellular therapeutics. In addition, he focuses on collaborations utilizing 3D technology like the Corning spheroid and Elplasia® microplates, Transwell® inserts and extracellular matrices to provide more predictive models for therapeutic response.