13571 Results for: "small b220"

Supplier: Tonbo Biosciences

The RA3-6B2 antibody reacts with the human and mouse CD45 isoform known as CD45R, or B220, a protein tyrosine phosphatase of 220 kDa. CD45 is one of the most abundant hematopoietic markers, and is expressed on all leukocytes (the Leukocyte Common Antigen, LCA). Various isoforms are generated and expressed in cell-specific patterns, all critical for leukocyte function. In mouse, the CD45R/B220 isoform is predominantly found on B cells, at varying levels on all stages from pro-B cells to activated B cells, and may also be detected on certain T cell and NK cell subsets. It is of note that B220 is not similarly expressed on human B cells, where it appears to be differentiation-specific and therefore expressed on only some B cell subsets. Other forms of CD45 with restricted cellular expression include CD45RA, CD45RB and CD45RO.

Supplier: BIOGEMS INTERNATIONAL INC.

The RA3-6B2 monoclonal antibody specifically reacts with a 220 kDa exon A-restricted epitope on the extracellular domain of mouse CD45 glycoprotein. CD45R/B220 is expressed on all the development stages of B cells, and at a low level on plasma cells and a subset of memory B cells. Low levels of CD45R/B220 are also expressed by some activated T lymphocytes, natural killer cell progenitors in the bone marrow, lymphokine activated killer cells (LAK), T lymphocytes of lpr/lpr mutant mouse, apoptotic T cells of mice injected with bacterial superantigens, and macrophage progenitors in fetal liver.The CD45 molecule is a member of the Protein Tyrosine Phosphatase (PTP) family, because its intracellular region contains two PTP domains. The extracellular region’s variability is caused by different levels of glycosylation, and the splicing of the 4, 5, and 6 exons. The isoforms found in the mouse strains depend on the activation state, maturation stage and cell type, and are very important in B and T lymphocytes antigen receptor signal transduction.The RA3-6B2 antibody inhibits in vivo B lymphocytes responses and enhances isotype switching during in vitro B lymphocyte responses.

Supplier: Biotium

CD45 / LCA Monoclonal antibody, Clone: 135-4C5, Host: Mouse, Species reactivity: Human, Isotype: IgG2b, kappa, Conjugate: CF647, Immunogen: Stimulated human leukocytes, Synonyms: B220, CD45R, Application: IF, IHC, FC, Size: 100uL

Supplier: Biotium

CD45 / LCA Monoclonal antibody, Clone: 136-4B5, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, Conjugate: CF405S, Immunogen: Stimulated human leukocytes, Synonyms: B220, CD45R, Application: IF, IHC, FC, Size: 100uL

Supplier: Biotium

CD45 / LCA Monoclonal antibody, Clone: 135-4C5, Host: Mouse, Species reactivity: Human, Isotype: IgG2b, kappa, Conjugate: CF680R, Immunogen: Stimulated human leukocytes, Synonyms: B220, CD45R, Application: IF, IHC, FC, Size: 100uL

Supplier: Biotium

CD45RB Monoclonal antibody, Clone: PTPRC/1132, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, Conjugate: CF568, Immunogen: Recom full-length human CD45RB protein, Synonyms: B220, CD45R, Application: IF, IHC, WB, FC, Size: 500 uL

Supplier: Biotium

CD45RB Monoclonal antibody, Clone: PTPRC/1147, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, Conjugate: CF647, Immunogen: Recom full-length human CD45RB protein, Synonyms: B220, CD45R, Application: IF, IHC, WB, FC, Size: 500 uL

Supplier: Biotium

CD45RB Monoclonal antibody, Clone: BRA-11G, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, Conjugate: purified, Immunogen: Non-T, non-B CALLA positive ALL cell line REH, Synonyms: B220, CD45R, Application: IF, IHC, FC, Size: 100uL

Supplier: Biotium

CD45RB Monoclonal antibody, Clone: PTPRC/1147, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, Conjugate: CF405S, Immunogen: Recom full-length human CD45RB protein, Synonyms: B220, CD45R, Application: IF, IHC, WB, FC, Size: 100uL

Supplier: Biotium

CD45RA Monoclonal antibody, Clone: PTPRC/1148, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, Conjugate: BSA-free, Immunogen: Recom full-length human CD45RA protein, Synonyms: B220, CD45R, Application: IF, IHC, FC, Size: 50 uL

Supplier: Biotium

CD45RB Monoclonal antibody, Clone: BRA-11G, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, Conjugate: CF568, Immunogen: Non-T, non-B CALLA positive ALL cell line REH, Synonyms: B220, CD45R, Application: IF, IHC, FC, Size: 100uL

Supplier: BIOGEMS INTERNATIONAL INC.

The RA3-6B2 monoclonal antibody specifically reacts with a 220 kDa exon A-restricted epitope on the extracellular domain of mouse CD45 glycoprotein. CD45R/B220 is expressed on all the development stages of B cells, and at a low level on plasma cells and a subset of memory B cells. Low levels of CD45R/B220 are also expressed by some activated T lymphocytes, natural killer cell progenitors in the bone marrow, lymphokine activated killer cells (LAK), T lymphocytes of lpr/lpr mutant mouse, apoptotic T cells of mice injected with bacterial superantigens, and macrophage progenitors in fetal liver.The CD45 molecule is a member of the Protein Tyrosine Phosphatase (PTP) family, because its intracellular region contains two PTP domains. The extracellular region’s variability is caused by different levels of glycosylation, and the splicing of the 4, 5, and 6 exons. The isoforms found in the mouse strains depend on the activation state, maturation stage and cell type, and are very important in B and T lymphocytes antigen receptor signal transduction.The RA3-6B2 antibody inhibits in vivo B lymphocytes responses and enhances isotype switching during in vitro B lymphocyte responses.

Supplier: Biotium

CD45RA Monoclonal antibody, Clone: 158-4D3, Host: Mouse, Species reactivity: Human, Isotype: IgG2a, kappa, Conjugate: biotin, Immunogen: Stimulated human leukocytes, Synonyms: B220, CD45R, Application: IF, IHC, FC, Size: 500 uL

Supplier: Biotium

CD45 / LCA Monoclonal antibody, Clone: 136-4B5, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, Conjugate: CF568, Immunogen: Stimulated human leukocytes, Synonyms: B220, CD45R, Application: IF, IHC, FC, Size: 100uL

Supplier: Biotium

CD45RA Monoclonal antibody, Clone: PTPRC/1131, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, Conjugate: CF594, Immunogen: Recom full-length human CD45RA protein, Synonyms: B220, CD45R, Application: IF, IHC, FC, Size: 500 uL

Supplier: Biotium

CD45RA Monoclonal antibody, Clone: PTPRC/1131, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, Conjugate: CF647, Immunogen: Recom full-length human CD45RA protein, Synonyms: B220, CD45R, Application: IF, IHC, FC, Size: 500 uL

Supplier: Biotium

CD45RA Monoclonal antibody, Clone: PTPRC/1148, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, Conjugate: CF640R, Immunogen: Recom full-length human CD45RA protein, Synonyms: B220, CD45R, Application: IF, IHC, FC, Size: 500 uL

Supplier: Biotium

CD45RB Monoclonal antibody, Clone: PTPRC/1147, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, Conjugate: CF568, Immunogen: Recom full-length human CD45RB protein, Synonyms: B220, CD45R, Application: IF, IHC, WB, FC, Size: 100uL

Supplier: Biotium

CD45RB Monoclonal antibody, Clone: PTPRC/1147, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, Conjugate: CF488A, Immunogen: Recom full-length human CD45RB protein, Synonyms: B220, CD45R, Application: IF, IHC, WB, FC, Size: 100uL

Supplier: Biotium

CD45RB Monoclonal antibody, Clone: PTPRC/1132, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, Conjugate: CF647, Immunogen: Recom full-length human CD45RB protein, Synonyms: B220, CD45R, Application: IF, IHC, WB, FC, Size: 100uL

Supplier: BIOGEMS INTERNATIONAL INC.

The RA3-6B2 monoclonal antibody specifically reacts with a 220 kDa exon A-restricted epitope on the extracellular domain of mouse CD45 glycoprotein. CD45R/B220 is expressed on all the development stages of B cells, and at a low level on plasma cells and a subset of memory B cells. Low levels of CD45R/B220 are also expressed by some activated T lymphocytes, natural killer cell progenitors in the bone marrow, lymphokine activated killer cells (LAK), T lymphocytes of lpr/lpr mutant mouse, apoptotic T cells of mice injected with bacterial superantigens, and macrophage progenitors in fetal liver.The CD45 molecule is a member of the Protein Tyrosine Phosphatase (PTP) family, because its intracellular region contains two PTP domains. The extracellular region’s variability is caused by different levels of glycosylation, and the splicing of the 4, 5, and 6 exons. The isoforms found in the mouse strains depend on the activation state, maturation stage and cell type, and are very important in B and T lymphocytes antigen receptor signal transduction.The RA3-6B2 antibody inhibits in vivo B lymphocytes responses and enhances isotype switching during in vitro B lymphocyte responses.

Supplier: Tonbo Biosciences

The RA3-6B2 antibody reacts with the human and mouse CD45 isoform known as CD45R, or B220, a protein tyrosine phosphatase of 220 kDa. CD45 is one of the most abundant hematopoietic markers, and is expressed on all leukocytes (the Leukocyte Common Antigen, LCA). Various isoforms are generated and expressed in cell-specific patterns, all critical for leukocyte function. In mouse, the CD45R/B220 isoform is predominantly found on B cells, at varying levels on all stages from pro-B cells to activated B cells, and may also be detected on certain T cell and NK cell subsets. It is of note that B220 is not similarly expressed on human B cells, where it appears to be differentiation-specific and therefore expressed on only some B cell subsets. Other forms of CD45 with restricted cellular expression include CD45RA, CD45RB and CD45RO.

Supplier: Biotium

CD45RA Monoclonal antibody, Clone: PTPRC/1148, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, Conjugate: CF594, Immunogen: Recom full-length human CD45RA protein, Synonyms: B220, CD45R, Application: IF, IHC, FC, Size: 100uL

Supplier: Biotium

CD45RA Monoclonal antibody, Clone: PTPRC/1148, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, Conjugate: CF568, Immunogen: Recom full-length human CD45RA protein, Synonyms: B220, CD45R, Application: IF, IHC, FC, Size: 100uL

Supplier: Biotium

CD45 / LCA Monoclonal antibody, Clone: 2B11 + PD7/26, Host: Mouse, Species reactivity: Human, Dog, Isotype: IgG's, Conjugate: CF594, Immunogen: Isolated neoplastic cells from T cell lymphoma, Synonyms: B220, CD45R, Application: IF, Size: 500 uL

Supplier: Biotium

CD45 / LCA Monoclonal antibody, Clone: 135-4C5, Host: Mouse, Species reactivity: Human, Isotype: IgG2b, kappa, Conjugate: CF660R, Immunogen: Stimulated human leukocytes, Synonyms: B220, CD45R, Application: IF, IHC, FC, Size: 100uL

Supplier: Biotium

CD45 / LCA Monoclonal antibody, Clone: 136-4B5, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, Conjugate: biotin, Immunogen: Stimulated human leukocytes, Synonyms: B220, CD45R, Application: IF, IHC, FC, Size: 100uL

Supplier: Biotium

CD45RB Monoclonal antibody, Clone: BRA-11G, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, Conjugate: CF640R, Immunogen: Non-T, non-B CALLA positive ALL cell line REH, Synonyms: B220, CD45R, Application: IF, IHC, FC, Size: 100uL

Supplier: Biotium

CD45RB Monoclonal antibody, Clone: BRA-11G, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, Conjugate: CF405S, Immunogen: Non-T, non-B CALLA positive ALL cell line REH, Synonyms: B220, CD45R, Application: IF, IHC, FC, Size: 100uL

Supplier: Biotium

CD45RA Monoclonal antibody, Clone: PTPRC/1131, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, Conjugate: CF488A, Immunogen: Recom full-length human CD45RA protein, Synonyms: B220, CD45R, Application: IF, IHC, FC, Size: 500 uL