670 Results for: "bmp"
Anti-GDF2 Rabbit Polyclonal Antibody (Alexa Fluor® 647)
Supplier: Bioss
The protein encoded by this gene is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Studies in rodents suggest that this protein plays a role in the adult liver and in differentiation of cholinergic central nervous system neurons. [provided by RefSeq, Jul 2008].
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Anti-BMP4 Rabbit Polyclonal Antibody
Supplier: ANTIBODIES.COM LLC
Rabbit polyclonal antibody to BMP-4 for WB and ELISA with samples derived from Human, Mouse and Rat.
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Anti-BMP7 Rabbit Polyclonal Antibody
Supplier: Proteintech
The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site.
BMP7, also known as osteogenic protein-1 or OP-1, plays a key role in the transformation of mesenchymal cells into bone and cartilage. BMP7 may be involved in bone homeostasis . It is expressed in the brain, kidneys and bladder. BMP7 is also present in cancers, including breast, prostate, and colon cancers, in which it is implicated in regulating cancer cell proliferation . Overexpression of BMP7 mRNA in colorectal cancer patients was significantly associated with poor prognosis and low overall survival . Recent studies suggest that high-expression level of BMP7 serves as a biomarker for poor prognosis for HCC .
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Human Recombinant BMF2 (from E. coli)
Supplier: Prosci
Human bone morphogenetic protein 2 (BMP2) is also known as human BMP-2, BMP-2, BMP2, BMP 2, h-BMP-2, rh-BMP-2, recombinant human BMP-2, recombinant BMP-2, BMP, is a member of the BMP subgroup belonging to the TGF-b superfamily of structurally related signaling proteins. BMP-2 is a potent osteoinductive cytokine, capable of inducing bone and cartilage formation in association with osteoconductive carriers such as collagen and synthetic hydroxyapatite. In addition to its osteogenic activity, BMP-2 plays an important role in cardiac morphogenesis and is expressed in a variety of tissues including lung, spleen, brain, liver, prostate ovary and small intestine. As implied by its name, BMPs promote and regulate bone development, growth, remodeling and repair, in both prenatal development and postnatal growth of eye, heart, kidney, skin, and other tissues. BMP2 has been demonstrated to potently induce osteoblast differentiation in a variety of cell types, and induce apoptosis in human myeloma cell lines as a novel function.
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Human Recombinant Twisted Gastrulation (TSG)
Supplier: Biolegend
Recombinant Twisted Gastrulation, Source: 293E cells, Reactivity: Human, Purity: >98%, Molecular Mass: 211 amino acid recombinant protein has a predicted molecular mass of approximately 23.6 kD, Application: Bioassay, Synonyms: Twisted Gastrulation BMP Signaling Modulator 1, Size: 100ug
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Human Recombinant TSG (from E. coli)
Supplier: Peprotech
Twisted Gastrulation Protein (TSG) is a secreted BMP-binding protein that is structurally related to the BMP antagonists Chordin and Noggin. TSG can inhibit BMP activity by binding directly to BMP proteins, and can act either as a BMP-4 agonist or antagonist (depending on the specific biochemical environment) by binding to the BMP-4/Chordin complex. Recombinant Human TSG is a 198 amino acid, 22.2 kDa protein containing the BMP-4/TGF-β binding portion of the full length TSG protein.
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Anti-BMP2+4 Rabbit Polyclonal Antibody
Supplier: ANTIBODIES.COM LLC
Rabbit polyclonal antibody to BMP-2 for WB, IHC and ELISA with samples derived from Human, Mouse and Rat.
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Mouse Bone MorphoGenetic Protein 4 (BMP-4) ELISA Kit, AFG Bioscience
Supplier: AFG BIOSCIENCE LLC
Mouse Bone MorphoGenetic Protein 4 (BMP-4) ELISA Kit, AFG Bioscience
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Human;Mouse;Rat Recombinant BMP-2 (from CHO cells)
Supplier: Peprotech
BMPs (Bone Morphogenetic Proteins) belong to the TGF-β superfamily of structurally related signaling proteins. BMP-2 is a potent osteoinductive cytokine, capable of inducing bone and cartilage formation in association with an osteoconductive carrier such as collagen and synthetic hydroxyapatite. In addition to its osteogenic activity, BMP-2 appears to play an important role in cardiac morphogenesis, and is expressed in a variety of other tissues, including lung, liver, spleen, prostate, ovary, and small intestine. The functional form of BMP-2 is a 26 kDa protein composed of two identical 114 amino acid polypeptide chains (monomers) linked by a single disulfide bond. Each BMP-2 monomer is expressed as the C-terminal part of a precursor polypeptide, which also contains a 23 amino acid signal sequence for secretion, and a 259 amino acid propeptide. After dimerization of this precursor, the covalent bonds between the propeptide (which is also a disulfide-linked homodimer) and the mature BMP-2 ligand are cleaved by a furin-type protease. Recombinant Human/Murine/Rat BMP-2 derived from
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Human BMP-binding Endothelial Regulator Protein (BMPER) ELISA Kit
Supplier: AFG BIOSCIENCE LLC
Human BMP-binding Endothelial Regulator Protein (BMPER) ELISA Kit
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Anti-CHRDL2 Rabbit Polyclonal Antibody (Alexa Fluor® 555)
Supplier: Bioss
CHRDL2 is a novel chordin like protein that can act as a BMP antagonist. Amember of the chordin family of proteins, it contains a signal peptide andthree CR (cysteine-rich repeat) domains. When expressed as a recombinantprotein it is secreted and binds to activin A, but not to BMP-2, -4, -6. Differential expression has been detected in developing chondrocytes, myoblasts, osteoblasts, and osteoarthritic joints. Complex alternative splicing of CHRDL2 potentially results in distinct isoforms that differ at their C termini, in the expression of signal peptide, and in the content of CR domains. CHRDL2 was originally characterized as a novel protein exclusively expressed in breast, lung, and colon tumors.
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Anti-CHRDL2 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))
Supplier: Bioss
CHRDL2 is a novel chordin like protein that can act as a BMP antagonist. Amember of the chordin family of proteins, it contains a signal peptide andthree CR (cysteine-rich repeat) domains. When expressed as a recombinantprotein it is secreted and binds to activin A, but not to BMP-2, -4, -6. Differential expression has been detected in developing chondrocytes, myoblasts, osteoblasts, and osteoarthritic joints. Complex alternative splicing of CHRDL2 potentially results in distinct isoforms that differ at their C termini, in the expression of signal peptide, and in the content of CR domains. CHRDL2 was originally characterized as a novel protein exclusively expressed in breast, lung, and colon tumors.
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Mouse Bone Morphogenetic Protein 15(BMP-15) ELISA Kit
Supplier: AFG BIOSCIENCE LLC
Mouse Bone Morphogenetic Protein 15(BMP-15) ELISA Kit
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Anti-GDF10 Rabbit Polyclonal Antibody (Alexa Fluor® 350)
Supplier: Bioss
GDF10, or growth differentiation factor 10, bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. GDF10 is expressed in femur, brain, lung, skeletal muscle, pancreas and testis.
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Human Recombinant GDF-6 (BMP-13)
Supplier: Biolegend
Recombinant GDF-6 (BMP-13), Source: E.coli, Reactivity: Human, Purity: >95%, Molecular Mass: 121 amino acid recombinant protein has a predicted molecular mass of approximately 13.7 kD, Application: Bioassay, Synonyms: GDF6, BMP13, CDMP-2, Growth/differentiation factor 6, Size: 25 ug
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Human Recombinant BMP2 (from CHO cells)
Supplier: Prosci
Bone morphogenetic protein 2 (BMP-2) is a member of the BMP subgroup of the TGF-beta superfamily. It plays a dominant role in embryonic dorsalventral patterning, organogenesis, limb bud formation and bone formation and regeneration. BMP-2 signals through heterodimeric complexes composed of a type I receptor (Activin RI, BMP-RIA or BMP-RIB) and a type II receptor (BMP-RII or Activin RIIB). BMP-2 induces chondrocyte proliferation, endochondral bone formation, longitudinal bone growth and bone and cartilage repair. It induces ectopic bone formation or calcification by promoting osteogenic and chondrogenic differentiation in mesenchymal cells, stem cells and vascular smooth muscle cells. It also promotes the maintenance and repair of colonic epithelium, suppresses neuronal dopamine synthesis and release, induces apoptosis in medulloblastoma cells and is required for cardiac contractility.
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Human BMP-15 ELISA Kit
Supplier: ANTIBODIES.COM LLC
This Human BMP-15 ELISA kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of Human BMP-15 in plasma, tissue homogenates and other biological fluids.
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Control Slides IHC BMP 10
Supplier: Mortech Manufacturing
All control slides are on Mopec IHC Enhanced Hydrophilic Adhesive Slides using Formalin Fixed Paraffin Embedded (FFPE) human tissue.
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Human Recombinant BMP-6 (from HEK293 cells)
Supplier: Peprotech
TGF-β family members are key modulators of cell proliferation, differentiation, matrix synthesis, and apoptosis. As implied by their name, BMPs initiate, promote, and regulate the development, growth, and remodeling of bone and cartilage. In addition to this role, BMPs are also involved in prenatal development and postnatal growth, remodeling, and maintenance of a variety of other tissues and organs. Increasing evidence indicates that BMP-Smad signaling has a tumor suppressing activity, and that BMPs can inhibit tumor growth. BMP-6 is abnormally expressed in breast cancer cell lines, however, its function in promoting breast cancer development is unknown. The mature and functional form of BMP-6 is a homodimer of two identical 139 amino acid polypeptide chains linked by a single disulfide bond. Each monomer is expressed as the C-terminal part of a precursor polypeptide, which contains a 20 amino acid signal peptide and a 354 amino acid propeptide. This precursor undergoes intracellular dimerization, and upon secretion it is processed by a furin-type protease. Recombinant Human BMP-6 is a 26.2 kDa homodimeric glycoprotein consisting of two 117 amino acid subunits, which correspond to amino acid residues 397 to 513 of the full-length BMP-6 precursor.
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Human/Murine/Rat BMP-2 Standard TMB ELISA Development Kit, PeproTech, Inc.
Supplier: Peprotech
PeproTech's Human/Murine/Rat BMP-2 ELISA development kit contains the key components required for the quantitative measurement of natural and/or recombinant h/m/rBMP-2 in a sandwich ELISA format.
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Human;Mouse;Rat Recombinant BMP-2 (from CHO cells)
Supplier: Peprotech
BMP-2 Recombinant, Purity: Greater than 95% by SDS-PAGE gel and HPLC, Source: CHO cells, Reactivity: Human, Molecular weight of approximately 28-29 kDa, Synonyms: Bone Morphogenetic Protein-2, BMP-2A, Size: 50 uG
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Anti-BMP-8 Rabbit Polyclonal Antibody
Supplier: ANTIBODIES.COM LLC
Rabbit polyclonal antibody to BMP-8 for IHC and ELISA with samples derived from Human.
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Mouse Bone Morphogenetic Protein 9,BMP-9 ELISA Kit
Supplier: AFG BIOSCIENCE LLC
Mouse Bone Morphogenetic Protein 9,BMP-9 ELISA Kit
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Mouse Bone Morphogenetic Protein 6,BMP-6 ELISA Kit
Supplier: AFG BIOSCIENCE LLC
Mouse Bone Morphogenetic Protein 6,BMP-6 ELISA Kit
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Human BMP-7 PicoKine ELISA Kit, Boster
Supplier: Boster Biological Technology
Sandwich ELISA kit of Quantitative Detection for Human BMP-7
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Rat Bone Morphogenetic Protein 2 (BMP-2) ELISA Kit
Supplier: AFG BIOSCIENCE LLC
Rat Bone Morphogenetic Protein 2 (BMP-2) ELISA Kit
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Rat Bone Morphogenetic Protein 7 (BMP-7) ELISA Kit
Supplier: AFG BIOSCIENCE LLC
Rat Bone Morphogenetic Protein 7 (BMP-7) ELISA Kit
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Human Bone Morphogenetic Protein 2(BMP-2) ELISA Kit 修改数据
Supplier: AFG BIOSCIENCE LLC
Human Bone Morphogenetic Protein 2(BMP-2) ELISA Kit 修改数据
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Anti-BMP2 Mouse Monoclonal Antibody [clone: 7B31]
Supplier: Genetex
Mouse monoclonal antibody [7B31] to BMP-2
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Human Recombinant BMP-13/CDMP-2 (from E. coli)
Supplier: Peprotech
BMP-13 is expressed in hypertrophic chondrocytes during embryonic development of long bones. Continued postnatal expression of BMP-13 in articular cartilage suggests that it plays a regulatory role in the growth and maintenance of articular cartilage. Adenovirus-mediated BMP-13 gene transfer to rabbit bone marrow stem cells have been reported to augment periosteal repair of osteochondral defects. The functional form of BMP-13/CDMP-2 is a disulfide-linked homodimer of two 120 amino-acid polypeptide chains. This 27.5 kDa protein is obtained by proteolytic processing of a biologically inactive precursor protein of 97.7 kDa. Recombinant Human BMP-13/CDMP-2 is a 27.0 kDa homodimeric disulfide-linked protein consisting of two 120 amino acid polypeptide chains.