670 Results for: "bmp"

Supplier: Rockland Immunochemical

Mouse BMP-2 AccuSignal ELISA Kit

Supplier: Peprotech

Bone morphogenetic proteins (BMPs) constitute a subfamily within the TGF-β superfamily of structurally related signaling proteins. Members of this superfamily are widely distributed throughout the body, and are involved in diverse physiological processes during both pre- and postnatal life. Like BMP-7, BMP-4 is involved in the development and maintenance of bone and cartilage. Reduced expression of BMP-4 is associated with a number of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. PeproTech’s

Supplier: ANTIBODIES.COM LLC

This Rat BMP-4 ELISA kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of Rat BMP-4 in plasma, tissue homogenates and other biological fluids.

Supplier: Peprotech

Monoclonal AntibodyProduced in mice immunized with highly pure Recombinant Human BMP-7. Anti­Human BMP-7­specific antibody was purified from cell culture by Protein G affinity chromatography.

Supplier: AFG BIOSCIENCE LLC

Rabbit Bone Morphgenetic Protein 2 (BMP-2) ELISA Kit, AFG Bioscience

Supplier: AFG BIOSCIENCE LLC

Mouse Bone MorphoGenetic Protein 7 (BMP-7) ELISA Kit, AFG Bioscience

Supplier: Peprotech

Monoclonal AntibodyProduced in mice immunized with highly pure Recombinant Human BMP-4. Anti­Human BMP-4­specific antibody was purified from cell culture by Protein G affinity chromatography.

Supplier: Boster Biological Technology

Sandwich ELISA kit of Quantitative Detection for Mouse BMP-2

Supplier: Peprotech

Animal-Free Human BMP-13/CDMP-2 Recombinant Protein, Purity: >95%, Source: E.coli, Biological Activity: Determined by its ability to induce alkaline phosphatase production by ATDC-5 cells, Synonyms

Supplier: Rockland Immunochemical

Human BMP-2 AccuSignal ELISA Kit

Supplier: Rockland Immunochemical

Mouse BMP-7 AccuSignal ELISA Kit

Supplier: Peprotech

Bone morphogenetic proteins (BMPs) constitute a subfamily within the TGF-β superfamily of structurally related signaling proteins. Members of this superfamily are widely distributed throughout the body, and are involved in diverse physiological processes during both pre- and postnatal life. Like BMP-7, BMP-4 is involved in the development and maintenance of bone and cartilage. Reduced expression of BMP-4 is associated with a number of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. Recombinant Human BMP-4, expressed in

Supplier: Peprotech

Bone morphogenetic proteins (BMPs) constitute a subfamily within the TGF-β superfamily of structurally related signaling proteins. Members of this superfamily are widely distributed throughout the body, and are involved in diverse physiological processes during both pre- and postnatal life. Like BMP-7, BMP-4 is involved in the development and maintenance of bone and cartilage. Reduced expression of BMP-4 is associated with a number of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. PeproTech’s

Supplier: Rockland Immunochemical

Human BMP-7 AccuSignal ELISA Kit

Supplier: Rockland Immunochemical

Human BMP-4 AccuSignal ELISA Kit

Supplier: Bioss

This gene encodes a secreted protein that interacts with, and inhibits bone morphogenetic protein (BMP) function. It has been shown to inhibit BMP2- and BMP4-dependent osteoblast differentiation and BMP-dependent differentiation of the chondrogenic cells. Mutations in this gene are associated with a lethal skeletal disorder, diaphanospondylodysostosis. [provided by RefSeq, Dec 2011].BMPER is a BMP-binding protein that is expressed by endothelial cell precursors, has BMP-antagonizing activity, and may play a role in endothelial cell differentiation by modulating local BMP activity. It may also regulate BMP responsiveness in osteoblasts and chondrocytes.

Supplier: ANTIBODIES.COM LLC

This Bovine BMP-7 ELISA kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of Bovine BMP-7.

Supplier: Prosci

BMPs (bone morphogenetic proteins) belong to the TGF beta superfamily of structurally related signaling proteins. Members of this superfamily are widely represented throughout the animal kingdom and have been implicated in a variety of developmental processes. Proteins of the TGF beta superfamily are disulfide-linked dimers composed of two 12-15 kDa polypeptide chains. As implied by their name, BMPs initiate, promote and regulate bone development, growth, remodeling and repair.

Supplier: Peprotech

PeproTech's Human/Murine/Rat BMP-2 ELISA development kit contains the key components required for the quantitative measurement of natural and/or recombinant human/murine/rat BMP-2 in a sandwich ELISA format.

Supplier: Rockland Immunochemical

Rat BMP-2 AccuSignal ELISA Kit

Supplier: Peprotech

TGF-β family members are key modulators of cell proliferation, differentiation, matrix synthesis, and apoptosis. As implied by their name, BMPs initiate, promote, and regulate the development, growth, and remodeling of bone and cartilage. In addition to this role, BMPs are also involved in prenatal development and postnatal growth, remodeling and maintenance of a variety of other tissues and organs. BMP-3 is abundantly found in adult bone and, to a lesser extent, fetal cartilage. BMP-3 inhibits osteogenesis and bone formation by activating a signaling cascade that antagonizes the signaling of pro-osteogenic BMPs. Recombinant Human BMP-3 is a disulfide-linked homodimeric protein that corresponds to residues 361 to 472 of the 472 amino acid BMP-3 precursor protein. The calculated molecular weight of Recombinant Human BMP-3 is 25.2 kDa.

Supplier: Peprotech

Bone morphogenetic proteins (BMPs) constitute a subfamily within the TGF-β superfamily of structurally related signaling proteins. Members of this superfamily are widely distributed throughout the body and are involved in diverse physiological processes during both pre- and postnatal life.  BMP-10 plays a crucial role in the development of the embryonic heart by acting to stimulate and maintain cardiomyocyte proliferation.  It can signal through various receptor complexes usually containing BMPR-1A, BMPR-1B, ALK1, ALK3, or ALK6. The interaction of BMP-10 with its specific receptors can induce signaling initiated by the phosphorylation of SMAD transcription factors, including SMAD1, SMAD5, or SMAD8, but can also induce SMAD independent processes.  BMP-10 is structurally related to BMP-9, and both can inhibit endothelial cell proliferation and migration. Recombinant Human BMP-10 is a 24.4 kDa homodimeric disulfide-linked protein consisting of two 108 amino acid subunits, which correspond to amino acid residues 317 to 424 of the full-length BMP-10 precursor.

Supplier: Rockland Immunochemical

Mouse BMP-4 AccuSignal ELISA Kit

Supplier: Peprotech

BMPs (Bone Morphogenetic Proteins) belong to the TGF-β superfamily of structurally related signaling proteins. BMP-2 is a potent osteoinductive cytokine, capable of inducing bone and cartilage formation in association with osteoconductive carriers such as collagen and synthetic hydroxyapatite. In addition to its osteogenic activity, BMP-2 plays an important role in cardiac morphogenesis, and is expressed in a variety of tissues, including lung, spleen, brain, liver, prostate ovary and small intestine. The functional form of BMP-2 is a 26 kDa protein composed of two identical 114 amino acid polypeptide chains linked by a single disulfide bond. Each BMP-2 monomer is expressed as the C-terminal part of a precursor polypeptide, which also contains a 23 amino acid signal sequence for secretion, and a 259 amino acid propeptide. After dimerization of this precursor, the covalent bonds between the propeptide (which is also a disulfide-linked homodimer) and the mature BMP-2 ligand are cleaved by a furin-type protease. Recombinant Human/Murine/Rat BMP-2 is a 26.0 kDa homodimeric protein consisting of two 115 amino acid polypeptide chains.

Supplier: Peprotech

TGF-β family members are key modulators of cell proliferation, differentiation, matrix synthesis, and apoptosis. As implied by their name, BMPs initiate, promote, and regulate the development, growth, and remodeling of bone and cartilage. In addition to this role, BMPs are also involved in prenatal development and postnatal growth, remodeling, and maintenance of a variety of other tissues and organs. BMP-5 is expressed in the nervous system, lungs and liver. It is a known regulator for dendritic growth in sympathetic neurons. BMP-5 is a 454 amino acid precursor protein that is cleaved to release the biologically active C-terminal mature protein. Recombinant Human BMP-5 is a 31.2 kDa homodimeric disulfide-linked protein consisting of two identical 138 amino acid chains.

Supplier: Rockland Immunochemical

Human BMP-5 AccuSignal ELISA Kit

Supplier: Bioss

On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Binds to BMP-7, BMP-2 and, less efficiently, BMP-4. Binding is weak but enhanced by the presence of type I receptors for BMPs.

Supplier: ANTIBODIES.COM LLC

This Mouse BMP-8B ELISA kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of Mouse BMP-8B in plasma, tissue homogenates and other biological fluids.

Supplier: Peprotech

BMP-4 Recombinant, Purity: Greater than 97% by SDS-PAGE gel and HPLC, Source: HeLa Cells, Reactivity: Human, Molecular mass of 25.6 kDa homodimeric glycoprotein, Synonyms: Bone Morphogenetic Protein-4, BMP-2B, DVR4, Size: 50 uG

Supplier: AFG BIOSCIENCE LLC

Rat Bone Morphogenetic Protein 6 (BMP-6) ELISA Kit