270 Results for: "assay 11-45"
Mouse Recombinant TIMP1
Supplier: Prosci
Tissue Inhibitor of Metalloproteinases 1 (TIMP-1) complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Also mediates erythropoiesis in vitro; but, unlike IL-3, it is species-specific, stimulating the growth and differentiation of only human and murine erythroid progenitors. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-11, MMP-12, MMP-13, and MMP-16. TIMP-1 does not act on MMP-14.
Expand 1 Items
Human Recombinant CCL27 (from E. coli)
Supplier: Prosci
Human Chemokine (C-C Motif) Ligand 27 (CCL27) is a small cytokine that is a member of the CC chemokine family; it is expressed in numerous tissues, including gonads, thymus, placenta and skin. CCL27 elicits its chemotactic effects by binding to the chemokine receptor CCR10. Predominantly expressed in the skin, CCL27 is associated with T cell-mediated inflammation of the skin. Human and Mouse CCL27 share 84% sequence identity in the mature form.
Expand 1 Items
Practice ELISA Kit, Cayman Chemical Company
Supplier: Cayman Chemical Company
A great alternative to learn Cayman’s AChE ELISA technology.
Expand 1 Items
![304503sfnew.jpg](https://occapi.avantorsciences.com/medias/304503sfnew.jpg?context=bWFzdGVyfGltYWdlc3wxMTYxOXxpbWFnZS9qcGVnfGFHTTJMMmhpWVM4NU56QTRPRFEzTXpNek5EQTJMek13TkRVd00zTm1ibVYzTG1wd1p3fGM3NjFjYjg1NDEwNzZmNTMyYWIyMTZiMmQ3MmRkNTY0NjQ1ZWUzZDRjMTk5NjE2MTI2MGRmMWUwMThkZTAzNWE)
FOCUS: SAFETY - OUT NOW!
Let’s enhance safety by considering personalized protection equipment (PPE) solutions tailored to your team, processes, and products.
Human Recombinant Transcriptional Repressor CTCF (from E. coli)
Supplier: Prosci
Transcriptional Repressor CTCF (CTCF) belongs to the CTCF Zinc-Finger Protein family. CTCF contains twelve C2H2-type zinc fingers and interacts with CHD8. CTCF is widely expressed in many tissues, and it is absent in primary spermatocytes. CTCF is involved in transcriptional regulation by binding to chromatin insulators and preventing interaction between promoter and nearby enhancers and silencers. CTCF plays an essential role in oocyte and preimplantation embryo development by activating or repressing transcription. In addition, CTCF is also indispensable in the epigenetic regulation and chromatin remodeling.
Expand 1 Items
Ultraviolet Photo-Oxidation Apparatus, Ace Glass Incorporated
Supplier: Ace Glass
Standard unit for liberation of inorganic phosphate from organically bound phosphorus compounds, oxidation of carbon in organic matter and oxidation of organic nitrogen compounds
Expand 7 Items
SpectraMax® M5/M5e Multimode Plate Reader, Molecular Devices
Supplier: Molecular Devices
The SpectraMax® M5 Multi-Mode Microplate Reader delivers single mode reader performance and can be equipped to read volumes as low as 2uL in one multimode reader package.
Expand 2 Items
VacTrap-G® (Glass) Vacuum Trap System, Foxx Life Sciences®
Supplier: Foxx Life Sciences
Vactrap™ G (Glass) vacuum trap system, adher to the strict CDC recommendation for laboratory safety.
Expand 3 Items
Anti-FAS Mouse Monoclonal Antibody [clone: DX2]
Supplier: Genetex
Mouse Monoclonal antibody [DX2] to Fas
Expand 1 Items
SMALP Screening Set
Supplier: CUBE BIOTECH
Membrane proteins and their composition are as versatile as the whole cell membrane itself. For this reason, it is impossible to predict with 100% accuracy which SMALP product is best suited for the solubilization and subsequent preparation of your membrane protein of interest. We offer this SMALP Screening Kit that consists of our four individual SMAs. This way, you can conveniently screen for the best SMA for your protein before scaling up your assay. In case you would like to extend your polymer screening beyond the reaches of SMA, we offer our Synthetic Nanodisc Screening Kit, which covers both SMA and DIBMA.
Expand 1 Items
Anti-PAI1 Mouse Monoclonal Antibody [clone: 3A120]
Supplier: Genetex
Mouse monoclonal antibody [3A120] to PAI-1
Expand 1 Items
Ore Sample Bags, Contract Sewing & Manufacturing
Supplier: CONTRACT SEWING & MANUFACTURING
Sample bags available in a variety of materials.
Expand 1 Items
Human Recombinant Myostatin Propeptide (from E. coli)
Supplier: Shenandoah Biotechnology
Myostatin (GDF-8), a member of the TGF-beta superfamily, is a potent and negative regulator of skeletal muscle mass. The recombinant myostatin propeptide binds and inhibits myostatin to enhance the repair and regeneration of injured muscle and bone.
Expand 4 Items
Anti-LPA3 Rabbit Polyclonal Antibody
Supplier: Genetex
EDG7 is a member of the G protein-coupled receptor family, as well as the EDG family of proteins. This protein functions as a cellular receptor for lysophosphatidic acid and mediates lysophosphatidic acid-evoked calcium mobilization. This receptor couples predominantly to G(q/11) alpha proteins.EDG7 has been reported in human prostate, as well as rodent brain, kidney, lung, placenta, prostate, and testis. ESTs have been isolated from a normal prostate library, as well as cancer libraries of the head/neck, ovary, and thyroid.
Expand 1 Items
DRG® Human Growth Hormone (HGH) ELISA, DRG International, Inc.
Supplier: DRG International
An enzyme immunoassay for the quantitative determination of human growth hormone (HGH) concentration in serum.
Expand 1 Items
Mouse Recombinant IL33 (from E. coli)
Supplier: Prosci
Mouse Interleukin 33 (IL-33) is a proinflammatory cytokine which may also regulates gene transcription in producer cells. IL-33 is structurally related to IL-1, which induces helper T cells to produce type 2 cytokines and acts through the receptor IL1RL-1. BindingIL-33 to this receptor activates NF-kappa-B and MAP kinases and induces in vitro Th2 cells to produce cytokines. In vivo, IL-33 induces the expression of IL-4, IL-5, IL-13 and also leads to severe pathological changes in mucosal organs.
Expand 1 Items
Anti-MCP3 Mouse Monoclonal Antibody [clone: 1015]
Supplier: Genetex
Clone: 1015 Purity: Protein G purified Species Reactivity: Human Tested Applications: ELISA, WB Pkg Size: 250 ug
Expand 1 Items
Thromboxane B₂ ELISA Kit, Cayman Chemical
Supplier: Cayman Chemical Company
For the quantification of TXB2 in urine, serum, tissue culture supernatants, and other sample matrices.
Expand 2 Items
Human Recombinant CGREF1 (from Cells)
Supplier: Prosci
Cell Growth Regulator with EF Hand Domain Protein 1 (CGREF1) is a secreted calcium ion binding protein. CGREF1 contains two EF-hand domains and both EF-hands are required for function. Human CGREF1 is synthesized as a 301 amino acid precursor that contains a 19 amino acid signal sequence, and a 282 amino acid mature chain. CGREF1 is probably digested extracellularly by an unknown serine protease generating extremely hydrophobic bioactive peptides. CGREF1 mediates cell-cell adhesion in a calcium-dependent manner. In addition, CGREF1 is able to inhibit growth in several cell lines.
Expand 1 Items
Quick-cfDNA/cfRNA Serum and Plasma Kit
Supplier: Zymo Research
The Quick-cfDNA/cfRNA Serum & Plasma Kit enables simple and efficient preparation of all circulating cell-free DNA and RNA (including protein-bound, exosomal, microRNA, and other small RNA) from serum, plasma, and other biological fluids, without using toxic phenol-chloroform or cumbersome protein precipitation and removal steps.
Expand 1 Items
Anti-APOC3 Goat Polyclonal Antibody
Supplier: Genetex
Biotin-conjugated Goat polyclonal to Apolipoprotein CIII (Biotin)
Expand 1 Items
Anti-LAMP2 Rat Monoclonal Antibody [clone: GL2A7]
Supplier: Genetex
Lysosomes are membrane-bound vacuoles which play a critical role in cellular metabolism. These organelles participate in endocytosis, the synthesis and assembly of acid hydrolases, act as sites for digestion of foreign materials and for specialized autolytic cellular processes. Membrane-associated glycoproteins have an important role in normal lysosomal function. Prior to posttranslational modification, Lysosome Associated Membrane Protein 2 (LAMP 2) is an ~45 kDa polypeptide. Mature, functional LAMP 2 is extensively glycosylated with a variety of different N-linked and O-linked oligosaccharides with a total molecular weight of ~100-110 kDa. LAMP 2 has a structure comprised of a large amino-terminal intra-lysosomal domain, a hydrophobic trans-membrane domain, and a short carboxyl-terminal cytoplasmic tail.
Expand 1 Items
Anti-PDE1C Rabbit Polyclonal Antibody
Supplier: Genetex
Cyclic nucleotides are hydrolyzed and compartmentalized by a family of enzymes called phosphodiesterases. In mammals at least 11 different families of PDEs can be discriminated (PDE1-11) based on their kinetic properties and inhibition to various pharmacological agents. Three different PDE1 genes have been identified (PDE1A, PDE1B, PDE1C). The enzymes of the PDE1A and PDE1B have higher affinity for cGMP than for cAMP, where as, PDE1C has high affinity for both cAMP and cGMP. Calcium-Calmodulin stimulates the activity of each of these enzymes several-fold. The PDE1C gene has been cloned from human, mouse and rat. The PDE1C gene codes a family of proteins (variants) that differ from each other at amino and carboxy termini of the protein. The tissue distribution of PDE1C is different from other PDE1 gene family members. A 5 splice variant of PDE1C2 is found in rat olfactory epithelium and is believed to be involved in olfactory signal transduction. Other PDE1C variants (PDE1C1 and PDE1C2) are found in human heart. The PDE1C enzymes bind both cGMP and cAMP with different affinities.
Expand 1 Items
SP Bel-Art Adjustable Microplate Tilting Stand, Bel-Art Products, a part of SP
Supplier: Bel-Art Products, a Part of SP
Make precise additions of liquid components to microplate wells by adjusting plates to the most convenient angle.
Expand 1 Items
Anti-IL8 Mouse Monoclonal Antibody [clone: I8-S2]
Supplier: Genetex
IL8, formerly called monocyte derived neutrophil chemotactic factor, belongs to the chemokine alpha family. Human endothelial IL8 is an 8.9 kDa protein containing 77 amino acid residues. IL8 exhibits chemotactic activity in vitro for T cells, basophils and neutrophils and promotes degranulation.
Expand 1 Items
HighSpec Rho Starter Set 3: HighSpec Compact Cartridge Rho1D4 + Rho1D4 Peptide
Supplier: CUBE BIOTECH
Our Rho1D4 starter set 3 combines our HighSpec Rho1D4 compact cartridge and the Rho1D4 elution peptide.
Expand 1 Items
Mouse IgG
Supplier: MP Biomedicals
Product is the lyophilized powder of mouse IgG and buffer salts.
Expand 1 Items
Human Recombinant IL33 (from E. coli)
Supplier: Prosci
Interleukin-33 (IL-33) is a recently identified member of the IL-1 family of cytokines whose other members include IL-1, IL-1Ra and IL-18 (1,2). Its receptor has been shown to be ST2, an IL-1 receptor family member that also acts as a negative regulator of TLR-IL-1R signaling (1,3) and IL-1R accessory protein (IL-1RAcP) (4). Receptor binding of IL-33 activates NF-B and MAP kinases and induces the expression of TH2-associated cytokines such as IL-4, IL-5 and IL-6. Prolonged IL-33 treatment of mice led to the development of eosinophilia, splenomegaly, and severe pathological changes in mucosal organs such as lungs, esophagus and small intestine (2). Recent experiments have shown that IL-33 can also co-localize with heterochromatin and possesses transcriptional repressor activities, indicating that IL-33 may function as both a proinflammatory cytokine and an intracellular nuclear factor with transcriptional regulatory properties (5). This recombinant protein represents the cleaved and presumably activated form of IL-33, but has not been tested in any biological assays.
Expand 1 Items
Human Recombinant CD3 epsilon (from Cells)
Supplier: Prosci
T-Cell Surface Glycoprotein CD3 epsilon Chain (CD3 epsilon ) is a single-pass type I membrane protein. CD3 epsilon contains 1 Ig-like (immunoglobulin-like) domain and 1 ITAM domain. CD3 epsilon is a polypeptide encoded by the CD3E gene on chromosome 11 in humans. The T cell receptor-CD3 complex (TCR/CD3 complex) is involved in T-cell development and several intracellular signal-transduction pathways. This complex is critical for T-cell development and function, and represents one of the most complex transmembrane receptors. The T cell receptor-CD3 complex is unique in having ten cytoplasmic immunoreceptor tyrosine-based activation motifs (ITAMs). TCR/CD3 complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways.
Expand 1 Items
Anti-IgG Donkey Polyclonal Antibody (TRITC (Tetramethylrhodamine Isothiocyanate))
Supplier: Immunoreagents
TRITC (Tetramethylrhodamine isothiocyanate) is a popular rhodamine derivative pink in color but emits a red-orange color upon Emission at 580nm. TRITC is frequently paired with FITC in double labeling experiments and conjugated antibodies are often used in immunofluorescence microscopy, flow cytometry, FLISA (fluorescent ELISA) and high throughput screening assays. These conjugates are best excited with the 532 nm spectral line of the He-Ne laser and are also recommended as a second color detection reagent in in situ hybridization applications. (Excitation/Emission = 555nm / 580nm Emission Color = Orange to Red (Similar Dyes: Alexa Fluor 555, Cy3, DyLight 550)
Expand 1 Items
Human Recombinant Ephrin Type-A Receptor 7 (from Cells)
Supplier: Prosci
Ephrin Type-A Receptor 7 (EPHA7) is a single-pass type I membrane protein which belongs to the Eph family of transmembrane receptor tyrosine kinases. It contains two fibronectin type-III domains, one protein kinase domain and one SAM (sterile alpha motif) domain. EPHA7 is a receptor for members of the ephrin-A family. Eph receptors are largely expressed throughout the ectoderm, mesoderm, and endoderm of vertebrate embryos. EPHA7 functions as a repulsive guidance molecule during the targeting of retinal axons to the superior colliculus and of neocortical axons to the thalamus. EPHA7 is expressed at a substantial level in most human lung cancers. The high expression of EPHA7 protein may participate in the malignancy transformation, invasion progression and metastasis of primary hepatocellular carcinoma. EPHA7 may involve in smoking related lung carcinogenesis.