4763 Results for: "SMALP b220"
Corrigé en : small b220
SARS-CoV-2 Recombinant SARS-CoV-2 Spike Protein in SMALP 200 (from HEK293 cells)
Supplier: CUBE BIOTECH
The coronavirus, also known as SARS-CoV-2, enters the cell by using its surface SPIKE. SPIKE is processed on the cell's surface by TMPRSS2, a serine protease. It then subsequently binds to ACE2 a cell surface receptor.
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SMALP BZ Screening Kit
Supplier: CUBE BIOTECH
SMALP BZs are synthesized via RAFT polymerization, achieving a better-defined polymer size and a low dispersity.
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SMALP Screening Set
Supplier: CUBE BIOTECH
Membrane proteins and their composition are as versatile as the whole cell membrane itself. For this reason, it is impossible to predict with 100% accuracy which SMALP product is best suited for the solubilization and subsequent preparation of your membrane protein of interest. We offer this SMALP Screening Kit that consists of our four individual SMAs. This way, you can conveniently screen for the best SMA for your protein before scaling up your assay. In case you would like to extend your polymer screening beyond the reaches of SMA, we offer our Synthetic Nanodisc Screening Kit, which covers both SMA and DIBMA.
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SMALP 140
Supplier: CUBE BIOTECH
The SMALP products have been developed for biomedical purposes, in particular, for the solubilization of (biological) lipid membranes and isolation & purification of integral membrane proteins.
After solving the SMA + buffer powder in water, the product is ready-to-use. It can primarily used for all cell membrane hosts, including bacteria, yeast, and human cells. After successful solubilization of the membrane protein, the protein can be purified using affinity chromatography. For membrane protein purification we recommend using the Rho1D4-tag. Cube Biotech offers matching products for this purpose.
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SMALP 140-I
Supplier: CUBE BIOTECH
The SMALP products have been developed for biomedical purposes, in particular, for the solubilization of (biological) lipid membranes and isolation & purification of integral membrane proteins.
After solving the SMA + buffer powder in water, the product is ready-to-use. It can primarily used for all cell membrane hosts, including bacteria, yeast, and human cells. After successful solubilization of the membrane protein, the protein can be purified using affinity chromatography. For membrane protein purification we recommend using the Rho1D4-tag. Cube Biotech offers matching products for this purpose.
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SMALP 200
Supplier: CUBE BIOTECH
The SMALP products have been developed for biomedical purposes, in particular, for the solubilization of (biological) lipid membranes and isolation & purification of integral membrane proteins.
After solving the SMA + buffer powder in water, the product is ready-to-use. It can primarily used for all cell membrane hosts, including bacteria, yeast, and human cells. After successful solubilization of the membrane protein, the protein can be purified using affinity chromatography. For membrane protein purification we recommend using the Rho1D4-tag. Cube Biotech offers matching products for this purpose.
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SMALP BZ25 Membrane protein solubilization & stabilization
Supplier: CUBE BIOTECH
The SMALP BZ series was developed in collaboration with Prof. Bert Klumperman from Nanosene, a spinout company of Stellenbosch University in South Africa. The goal was to create SMALPs that are synthesized via RAFT polymerization, achieving a better defined polymer size and a low dispersity (narrow chain length distribution). This is a significant improvement over previous SMALPs. The SMALP BZs are thus more efficient in dissolving the cell membranes and increasing protein yield.
After successful solubilization of the membrane protein, the protein can be purified using affinity chromatography. For membrane protein purification we recommend using the Rho1D4-tag. Cube Biotech offers matching products for this purpose.
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SMALP 300
Supplier: CUBE BIOTECH
The SMALP products have been developed for biomedical purposes, in particular, for the solubilization of (biological) lipid membranes and isolation & purification of integral membrane proteins.
After solving the SMA + buffer powder in water, the product is ready-to-use. It can primarily used for all cell membrane hosts, including bacteria, yeast, and human cells. After successful solubilization of the membrane protein, the protein can be purified using affinity chromatography. For membrane protein purification we recommend using the Rho1D4-tag. Cube Biotech offers matching products for this purpose.
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SMALP BZ30 Membrane protein solubilization & stabilization
Supplier: CUBE BIOTECH
The SMALP BZ series was developed in collaboration with Prof. Bert Klumperman from Nanosene, a spinout company of Stellenbosch University in South Africa. The goal was to create SMALPs that are synthesized via RAFT polymerization, achieving a better defined polymer size and a low dispersity (narrow chain length distribution). This is a significant improvement over previous SMALPs. The SMALP BZs are thus more efficient in dissolving the cell membranes and increasing protein yield.
After successful solubilization of the membrane protein, the protein can be purified using affinity chromatography. For membrane protein purification we recommend using the Rho1D4-tag. Cube Biotech offers matching products for this purpose.
Expand 3 Items
SMALP BZ40 Membrane protein solubilization & stabilization
Supplier: CUBE BIOTECH
The SMALP BZ series was developed in collaboration with Prof. Bert Klumperman from Nanosene, a spinout company of Stellenbosch University in South Africa. The goal was to create SMALPs that are synthesized via RAFT polymerization, achieving a better defined polymer size and a low dispersity (narrow chain length distribution). This is a significant improvement over previous SMALPs. The SMALP BZs are thus more efficient in dissolving the cell membranes and increasing protein yield.
After successful solubilization of the membrane protein, the protein can be purified using affinity chromatography. For membrane protein purification we recommend using the Rho1D4-tag. Cube Biotech offers matching products for this purpose.
Expand 3 Items
SMALP BZ35 Membrane protein solubilization & stabilization
Supplier: CUBE BIOTECH
The SMALP BZ series was developed in collaboration with Prof. Bert Klumperman from Nanosene, a spinout company of Stellenbosch University in South Africa. The goal was to create SMALPs that are synthesized via RAFT polymerization, achieving a better defined polymer size and a low dispersity (narrow chain length distribution). This is a significant improvement over previous SMALPs. The SMALP BZs are thus more efficient in dissolving the cell membranes and increasing protein yield.
After successful solubilization of the membrane protein, the protein can be purified using affinity chromatography. For membrane protein purification we recommend using the Rho1D4-tag. Cube Biotech offers matching products for this purpose.
Expand 3 Items
SARS-CoV-2 Recombinant SARS-CoV-2 Spike Protein in SMALP 140 (from HEK293 cells)
Supplier: CUBE BIOTECH
The coronavirus, also known as SARS-CoV-2, enters the cell by using its surface SPIKE. SPIKE is processed on the cell's surface by TMPRSS2, a serine protease. It then subsequently binds to ACE2 a cell surface receptor.
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Anti-CD45R Rat Monoclonal Antibody (APC-Cyanine7) [clone: RA3-6B2]
Supplier: Tonbo Biosciences
The RA3-6B2 antibody reacts with the human and mouse CD45 isoform known as CD45R, or B220, a protein tyrosine phosphatase of 220 kDa. CD45 is one of the most abundant hematopoietic markers, and is expressed on all leukocytes (the Leukocyte Common Antigen, LCA). Various isoforms are generated and expressed in cell-specific patterns, all critical for leukocyte function. In mouse, the CD45R/B220 isoform is predominantly found on B cells, at varying levels on all stages from pro-B cells to activated B cells, and may also be detected on certain T cell and NK cell subsets. It is of note that B220 is not similarly expressed on human B cells, where it appears to be differentiation-specific and therefore expressed on only some B cell subsets. Other forms of CD45 with restricted cellular expression include CD45RA, CD45RB, CD45RO and several others. The RA3-6B2 antibody is one of the most consistently used leukocyte markers for B cells, T cell subsets and NK cell subsets in human and mouse. This antibody has also been reported as cross-reactive with feline CD45R/B220.
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Anti-PTPRC Mouse Monoclonal Antibody (CF488A) [clone: 158-4D3]
Supplier: Biotium
CD45RA Monoclonal antibody, Clone: 158-4D3, Host: Mouse, Species reactivity: Human, Isotype: IgG2a, kappa, Conjugate: CF488A, Immunogen: Stimulated human leukocytes, Synonyms: B220, CD45R, Application: IF, IHC, FC, Size: 100uL
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Anti-PTPRC Mouse Monoclonal Antibody (CF594) [clone: 135-4C5]
Supplier: Biotium
CD45 / LCA Monoclonal antibody, Clone: 135-4C5, Host: Mouse, Species reactivity: Human, Isotype: IgG2b, kappa, Conjugate: CF594, Immunogen: Stimulated human leukocytes, Synonyms: B220, CD45R, Application: IF, IHC, FC, Size: 100uL
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Anti-CD45R/B220 Rat Monoclonal Antibody [clone: RA3-6B2] (Spark NIR™ 685)
Supplier: Biolegend
CD45R/B220 Monoclonal Antibody, Clone: RA3-6B2, Host: Rat, Species reactivity: Mouse, Isotype: IgG2a, K, Conjugate: SparkNIR 685, Immunogen: Abelson murine leukemia virus-induced pre-B tumor cell, Formulation: Phosphate-buffered solution, pH 7.2, Synonyms: B220, Application: FC, Size: 100 ug
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Anti-PTPRC Mouse Monoclonal Antibody [clone: PTPRC/1131]
Supplier: Biotium
CD45RA Monoclonal antibody, Clone: PTPRC/1131, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, Conjugate: BSA-free, Immunogen: Recom full-length human CD45RA protein, Synonyms: B220, CD45R, Application: IF, IHC, FC, Size: 50 uL
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Anti-PTPRC Mouse Monoclonal Antibody (CF647) [clone: 2B11 PD7/26]
Supplier: Biotium
CD45 / LCA Monoclonal antibody, Clone: 2B11 + PD7/26, Host: Mouse, Species reactivity: Human, Dog, Isotype: IgG's, Conjugate: CF647, Immunogen: Isolated neoplastic cells from T cell lymphoma, Synonyms: B220, CD45R, Application: IF, Size: 100uL
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Anti-PTPRC Mouse Monoclonal Antibody (Biotin) [clone: BRA-11G]
Supplier: Biotium
CD45RB Monoclonal antibody, Clone: BRA-11G, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, Conjugate: biotin, Immunogen: Non-T, non-B CALLA positive ALL cell line REH, Synonyms: B220, CD45R, Application: IF, IHC, FC, Size: 100uL
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Anti-PTPRC Mouse Monoclonal Antibody (CF594) [clone: PTPRC/1132]
Supplier: Biotium
CD45RB Monoclonal antibody, Clone: PTPRC/1132, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, Conjugate: CF594, Immunogen: Recom full-length human CD45RB protein, Synonyms: B220, CD45R, Application: IF, IHC, WB, FC, Size: 500 uL
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Anti-PerCP-Cy5.5 Anti-Human/MouseCD45R (B220) (RA3-6B2) Rat Monoclonal Antibody (PerCP (Peridinin-Chlorophyll Protein Complex)-Cy5.5®) [clone: RA3-6B2]
Supplier: BIOGEMS INTERNATIONAL INC.
The RA3-6B2 monoclonal antibody specifically reacts with a 220 kDa exon A-restricted epitope on the extracellular domain of mouse CD45 glycoprotein. CD45R/B220 is expressed on all the development stages of B cells, and at a low level on plasma cells and a subset of memory B cells. Low levels of CD45R/B220 are also expressed by some activated T lymphocytes, natural killer cell progenitors in the bone marrow, lymphokine activated killer cells (LAK), T lymphocytes of lpr/lpr mutant mouse, apoptotic T cells of mice injected with bacterial superantigens, and macrophage progenitors in fetal liver.The CD45 molecule is a member of the Protein Tyrosine Phosphatase (PTP) family, because its intracellular region contains two PTP domains. The extracellular region’s variability is caused by different levels of glycosylation, and the splicing of the 4, 5, and 6 exons. The isoforms found in the mouse strains depend on the activation state, maturation stage and cell type, and are very important in B and T lymphocytes antigen receptor signal transduction.The RA3-6B2 antibody inhibits in vivo B lymphocytes responses and enhances isotype switching during in vitro B lymphocyte responses.
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Anti-PE-Cy5 Anti-Human/MouseCD45R (B220) (RA3-6B2) Rat Monoclonal Antibody (PE (Phycoerythrin)-Cy5®) [clone: RA3-6B2]
Supplier: BIOGEMS INTERNATIONAL INC.
The RA3-6B2 monoclonal antibody specifically reacts with a 220 kDa exon A-restricted epitope on the extracellular domain of mouse CD45 glycoprotein. CD45R/B220 is expressed on all the development stages of B cells, and at a low level on plasma cells and a subset of memory B cells. Low levels of CD45R/B220 are also expressed by some activated T lymphocytes, natural killer cell progenitors in the bone marrow, lymphokine activated killer cells (LAK), T lymphocytes of lpr/lpr mutant mouse, apoptotic T cells of mice injected with bacterial superantigens, and macrophage progenitors in fetal liver.The CD45 molecule is a member of the Protein Tyrosine Phosphatase (PTP) family, because its intracellular region contains two PTP domains. The extracellular region’s variability is caused by different levels of glycosylation, and the splicing of the 4, 5, and 6 exons. The isoforms found in the mouse strains depend on the activation state, maturation stage and cell type, and are very important in B and T lymphocytes antigen receptor signal transduction.The RA3-6B2 antibody inhibits in vivo B lymphocytes responses and enhances isotype switching during in vitro B lymphocyte responses.
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Anti-PTPRC Rat Antibody (redFluor® 710) [clone: RA3-6B2]
Supplier: Tonbo Biosciences
The RA3-6B2 antibody reacts with the human and mouse CD45 isoform known as CD45R, or B220, a protein tyrosine phosphatase of 220 kDa. CD45 is one of the most abundant hematopoietic markers, and is expressed on all leukocytes (the Leukocyte Common Antigen, LCA). Various isoforms are generated and expressed in cell-specific patterns, all critical for leukocyte function. In mouse, the CD45R/B220 isoform is predominantly found on B cells, at varying levels on all stages from pro-B cells to activated B cells, and may also be detected on certain T cell and NK cell subsets. It is of note that B220 is not similarly expressed on human B cells, where it appears to be differentiation-specific and therefore expressed on only some B cell subsets. Other forms of CD45 with restricted cellular expression include CD45RA, CD45RB and CD45RO.
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Anti-PTPRC Rat Monoclonal Antibody [clone: RA3-6B2]
Supplier: Tonbo Biosciences
The RA3-6B2 antibody reacts with the human and mouse CD45 isoform known as CD45R, or B220, a protein tyrosine phosphatase of 220 kDa. CD45 is one of the most abundant hematopoietic markers, and is expressed on all leukocytes (the Leukocyte Common Antigen, LCA). Various isoforms are generated and expressed in cell-specific patterns, all critical for leukocyte function. In mouse, the CD45R/B220 isoform is predominantly found on B cells, at varying levels on all stages from pro-B cells to activated B cells, and may also be detected on certain T cell and NK cell subsets. It is of note that B220 is not similarly expressed on human B cells, where it appears to be differentiation-specific and therefore expressed on only some B cell subsets. Other forms of CD45 with restricted cellular expression include CD45RA, CD45RB and CD45RO.
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Anti-PTPRC Rat Monoclonal Antibody (FITC (Fluorescein Isothiocyanate)) [clone: RA3-6B2]
Supplier: Tonbo Biosciences
The RA3-6B2 antibody reacts with the human and mouse CD45 isoform known as CD45R, or B220, a protein tyrosine phosphatase of 220 kDa. CD45 is one of the most abundant hematopoietic markers, and is expressed on all leukocytes (the Leukocyte Common Antigen, LCA). Various isoforms are generated and expressed in cell-specific patterns, all critical for leukocyte function. In mouse, the CD45R/B220 isoform is predominantly found on B cells, at varying levels on all stages from pro-B cells to activated B cells, and may also be detected on certain T cell and NK cell subsets. It is of note that B220 is not similarly expressed on human B cells, where it appears to be differentiation-specific and therefore expressed on only some B cell subsets. Other forms of CD45 with restricted cellular expression include CD45RA, CD45RB and CD45RO.
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Anti-PTPRC Rat Monoclonal Antibody (PE (Phycoerythrin)) [clone: RA3-6B2]
Supplier: Tonbo Biosciences
The RA3-6B2 antibody reacts with the human and mouse CD45 isoform known as CD45R, or B220, a protein tyrosine phosphatase of 220 kDa. CD45 is one of the most abundant hematopoietic markers, and is expressed on all leukocytes (the Leukocyte Common Antigen, LCA). Various isoforms are generated and expressed in cell-specific patterns, all critical for leukocyte function. In mouse, the CD45R/B220 isoform is predominantly found on B cells, at varying levels on all stages from pro-B cells to activated B cells, and may also be detected on certain T cell and NK cell subsets. It is of note that B220 is not similarly expressed on human B cells, where it appears to be differentiation-specific and therefore expressed on only some B cell subsets. Other forms of CD45 with restricted cellular expression include CD45RA, CD45RB and CD45RO.
Expand 2 Items
Anti-PE-Cy5 Anti-Human/MouseCD45R (B220) (RA3-6B2) Rat Monoclonal Antibody (PE (Phycoerythrin)-Cy5®) [clone: RA3-6B2]
Supplier: BIOGEMS INTERNATIONAL INC.
The RA3-6B2 monoclonal antibody specifically reacts with a 220 kDa exon A-restricted epitope on the extracellular domain of mouse CD45 glycoprotein. CD45R/B220 is expressed on all the development stages of B cells, and at a low level on plasma cells and a subset of memory B cells. Low levels of CD45R/B220 are also expressed by some activated T lymphocytes, natural killer cell progenitors in the bone marrow, lymphokine activated killer cells (LAK), T lymphocytes of lpr/lpr mutant mouse, apoptotic T cells of mice injected with bacterial superantigens, and macrophage progenitors in fetal liver.The CD45 molecule is a member of the Protein Tyrosine Phosphatase (PTP) family, because its intracellular region contains two PTP domains. The extracellular region’s variability is caused by different levels of glycosylation, and the splicing of the 4, 5, and 6 exons. The isoforms found in the mouse strains depend on the activation state, maturation stage and cell type, and are very important in B and T lymphocytes antigen receptor signal transduction.The RA3-6B2 antibody inhibits in vivo B lymphocytes responses and enhances isotype switching during in vitro B lymphocyte responses.
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Anti-Ptprc Rat Monoclonal Antibody [clone: RA3.3A1/6.1 (TIB-146)]
Supplier: Genetex
Rat monoclonal antibody [RA3.3A1/6.1 (TIB-146)] to CD45R
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Anti-CD45R Rat Monoclonal Antibody (APC (Allophycocyanin)) [clone: RA3-6B2]
Supplier: BIOGEMS INTERNATIONAL INC.
The RA3-6B2 monoclonal antibody specifically reacts with a 220 kDa exon A-restricted epitope on the extracellular domain of mouse CD45 glycoprotein. CD45R/B220 is expressed on all the development stages of B cells, and at a low level on plasma cells and a subset of memory B cells. Low levels of CD45R/B220 are also expressed by some activated T lymphocytes, natural killer cell progenitors in the bone marrow, lymphokine activated killer cells (LAK), T lymphocytes of lpr/lpr mutant mouse, apoptotic T cells of mice injected with bacterial superantigens, and macrophage progenitors in fetal liver.The CD45 molecule is a member of the Protein Tyrosine Phosphatase (PTP) family, because its intracellular region contains two PTP domains. The extracellular region’s variability is caused by different levels of glycosylation, and the splicing of the 4, 5, and 6 exons. The isoforms found in the mouse strains depend on the activation state, maturation stage and cell type, and are very important in B and T lymphocytes antigen receptor signal transduction.The RA3-6B2 antibody inhibits in vivo B lymphocytes responses and enhances isotype switching during in vitro B lymphocyte responses.
Expand 1 Items
Anti-CD45R Rat Monoclonal Antibody (FITC (Fluorescein Isothiocyanate)) [clone: RA3-6B2]
Supplier: BIOGEMS INTERNATIONAL INC.
The RA3-6B2 monoclonal antibody specifically reacts with a 220 kDa exon A-restricted epitope on the extracellular domain of mouse CD45 glycoprotein. CD45R/B220 is expressed on all the development stages of B cells, and at a low level on plasma cells and a subset of memory B cells. Low levels of CD45R/B220 are also expressed by some activated T lymphocytes, natural killer cell progenitors in the bone marrow, lymphokine activated killer cells (LAK), T lymphocytes of lpr/lpr mutant mouse, apoptotic T cells of mice injected with bacterial superantigens, and macrophage progenitors in fetal liver.The CD45 molecule is a member of the Protein Tyrosine Phosphatase (PTP) family, because its intracellular region contains two PTP domains. The extracellular region’s variability is caused by different levels of glycosylation, and the splicing of the 4, 5, and 6 exons. The isoforms found in the mouse strains depend on the activation state, maturation stage and cell type, and are very important in B and T lymphocytes antigen receptor signal transduction.The RA3-6B2 antibody inhibits in vivo B lymphocytes responses and enhances isotype switching during in vitro B lymphocyte responses.