1119 Results for: "Genscript"

Supplier: Genscript

GenScript mouse anti-rabbit IgG Fc antibody (14H9), mAb reacts with the Fc portion of rabbit IgG but not with the Fab portion of rabbit IgG. The monoclonal antibody has no cross-reactivity with human, mouse, rat, sheep, bovine, goat or camel immunoglobulins.

Supplier: Genscript

GenBox Gel electrophoresis system is designed to run 1 or 2 mini gels at the same time. GenBox mini tank is designed for ultimate convenience and consistent performance compared to traditional electrophoresis tanks. Discover the versatile and easy to use GenBox mini tank for your gel electrophoresis and blotting needs.

Supplier: Genscript

The product is specific for palivizumab.

Supplier: Genscript

The product is specific for SARS-CoV-2 RBD domain.The product can neutralize Wild-Type SARS-CoV-2 and Variants of Concern (VOC) including Alpha, Beta, Gamma, Delta, but can't neutralize Omicron BA.1, Omicron BA.2 and Omicron BA.4/BA.5.

Supplier: Genscript

The product is specific for Ipilimumab. The antibody is recommended as a capture antibody in a pharmacokinetic (PK) bridging assay with detection antibody GenScript, A01858-40, Anti- Ipilimumab Antibody (4H6E1D4), mAb, Mouse.

Supplier: Genscript

The product is specific for Adalimumab. This antibody serves as an excellent positive control for Adalimumab The product is specific for Adalimumab. This antibody serves as an excellent positive control for Adalimumab immunogenicity (ADA) assays.

Supplier: Genscript

GenScript Mouse Anti-Human IgG Fc Antibody (50B4A9)[HRP], mAb reacts with the Fc portion of human IgG but not with the Fab portion of human IgG. This monoclonal antibody has no cross-reactivity with mouse, rat, rabbit, chicken or goat immunoglobulins.

Supplier: Genscript

The product is specific for Bevacizumab. This antibody serves as an excellent positive control for Bevacizumab immunogenicity (ADA) assays.

Supplier: Genscript

The product is specific for Bevacizumab. This antibody blocks Bevacizumab binding with VEGF165 (Z02689, VEGF165, Human). The antibody is recommended as a detection antibody in a pharmacokinetic (PK) bridging assay with capture antibody GenScript, A01895-40, MonoRabTM Anti-Bevacizumab Antibody (30E1), mAb, Rabbit.

Supplier: Genscript

PAGE-MASTER Protein Standard, Consists of seven bands with molecular weight of 10 kD, 20 kD, 30 kD, 40 kD, 60 kD, 80 kD and 120 kD, All bands are highly purified, Volume: Load 5 ul/well for a mini-gel, Application: For SDS-PAGE gels, Storage: -20deg C, Size: 500ul

Supplier: Genscript

The product is specific for Nivolumab. The antibody is recommended as a detection antibody in a pharmacokinetic (PK) bridging assay with capture antibody GenScript, A01847-40, Anti- Nivolumab Antibody (8G6G3D8), mAb, Mouse.

Supplier: Genscript

GenScript His-tag antibody, pAb, Rabbit specifically reacts with fusion proteins containing His epitope tags.For N-terminal His-tagged protein detection, THE™ Anti-His mAb (Cat.No.A00186) is recommended.

Supplier: Genscript

Protein A, a bacterial cell wall protein isolated from Staphylococcus aureus, binds to mammalian IgGs mainly through Fc regions. The Protein A is most commonly bound to a chromatography resin, used for production of antibody drugs or reagents. Protein A antibody can be used for quantification of Protein A in drugs and foods or for evaluation of Protein A resin. This Protein A mAb is advantageous due to its IgG1 isotype, for mouse IgG1 has weak binding capacity to Protein A. GenScript Protein A Antibody, mAb, Mouse is produced from the hybridoma resulting from fusion of SP2/0-Ag14 myeloma and B-lymphocytes obtained from mouse immunized with purified recombinant Protein A.

Supplier: Genscript

GenScript Rabbit Anti-GST-tag Polyclonal Antibody is highly purified from rabbit antiserum by immunoaffinity chromatography. The immunogen used is a recombinant version of glutathione-S-transferase from Schistosoma japonicum. Glutathione-S-transferase is an epitope tag in generating fusion proteins. Antibodies specific to fusion proteins are useful in monitoring protein expression in Western Blots as well as immunoaffinity purification of proteins expressed in E. coli. The glutathione-S-transferases are a family of enzymes that catalyze the addition of the tripeptide glutathione to endogenous and xenobiotic substrates which have electrophilic functional groups. They play an important role in the detoxication and metabolism of many xenobiotic and endobiotic compounds. The glutathione adducts produced have increased solubility in water and are subsequently enzymatically degraded to mercapturates and excreted.

Supplier: Genscript

A camelid single-domain antibody (sdAb, called Nanobody by Ablynx, the developer) is a peptide chain of about 110 amino acids long, comprising one variable domain of a heavy-chain antibody, these are called VHH fragments. Like a whole antibody, it is able to bind selectively to a specific antigen. Single-domain antibodies allow a broad range of applications in biotechnical as well as therapeutic uses due to their small size, simple production, and high affinity. However, their sequences may increase the risk of immunogenicity and anti-drug antibody (ADA) development in humans, and thus, sdAbs are routinely humanized during development.

Supplier: Genscript

A camelid single-domain antibody (sdAb, called Nanobody by Ablynx, the developer) is a peptide chain of about 110 amino acids long, comprising one variable domain of a heavy-chain antibody, these are called VHH fragments. Like a whole antibody, it is able to bind selectively to a specific antigen. Single-domain antibodies allow a broad range of applications in biotechnical as well as therapeutic uses due to their small size, simple production, and high affinity. However, their sequences may increase the risk of immunogenicity and anti-drug antibody (ADA) development in humans, and thus, sdAbs are routinely humanized during development.

Supplier: Genscript

Palivizumab with trade name Synagis, is an FDA-approved drug for the prevention of respiratory syncytial virus (RSV) infections. It is a recombinant humanized IgG1 kappa isotype monoclonal antibody. Palivizumab binds the RSV envelope fusion protein (RSV F) on the surface of the virus and blocking a critical step in the membrane fusion process. Anti-Palivizumab Antibody (7B3), mAb, Mouse is produced from a hybridoma resulting from the fusion of partner and B-lymphocytes obtained from a mouse immunized with Palivizumab.

Supplier: Genscript

Ustekinumab with trade name Stelara, is an FDA-approved drug to Crohn's disease, Ulcerative Colitis, Plaque Psoriasis and Psoriatic Arthritis, targeting both interleukins (IL)-12 and IL-23. Ustekinumab is a fully human immunoglobulin G1 kappa mAb that binds to IL-12 and IL-23. Ustekinumab binds to the p40 subunit common to IL-12 and IL-23 and prevents their interaction with the IL-12 receptor β1 subunit of the IL-12 and IL-23 receptor complexes, thereby disrupting the proinflammatory pathway. Anti-Ustekinumab Antibody (5F9), mAb, Mouse is produced from a hybridoma resulting from the fusion of partner and B-lymphocytes obtained from a mouse immunized with Ustekinumab.

Supplier: Genscript

Adeno-associated virus type 2 (AAV2) is a valuable vector for gene therapy. It is one member of the human parvovirus family which depends on co-infection with helper viruses such as adenovirus or herpes virus for efficient reproduction. AAV2 empty capsids are composed of three proteins, VP1, VP2 and VP3 with relative molecular masses of 87, 72 and 62 kDa respectively.

Supplier: Genscript

SARS-CoV-2 (Severe acute respiratory syndrome coronavirus 2), also known as 2019-nCoV, is a positive-sense single-stranded RNA virus. It caused coronavirus disease 2019 (COVID-19). SARS-CoV-2 contains glycosylated spike (S) protein, which is composed of S1 subunit and S2 subunit. The S1 contains a receptor-binding domain (RBD) that can bind to ACE2 receptor on target cells. Lineage B.1.617 has the double mutations E484Q and L452R in the spikeproteins.

Supplier: Genscript

Dupilumab with trade name dupixent, is an FDA-approved drug for the treatment of patients aged six years and older with moderate-to-severe atopic dermatitis. It is a human monoclonal antibody. Dupilumab binds to the interleukin-4 receptor alpha (IL-4R alpha) subunit shared by the interleukin (IL)-4 and IL-13 receptor complexes, thereby inhibiting IL-4 and IL-13 signaling. Anti-Dupilumab Antibody (6C9), mAb, Mouse is produced from a hybridoma resulting from the fusion of partner and B-lymphocytes obtained from a mouse immunized with dupilumab.

Supplier: Genscript

Adeno-associated virus type 2 (AAV2) is a valuable vector for gene therapy. It is one member of the human parvovirus family which depends on co-infection with helper viruses such as adenovirus or herpes virus for efficient reproduction. AAV2 empty capsids are composed of three proteins, VP1, VP2 and VP3 with relative molecular masses of 87, 72 and 62 kDa, respectively.

Supplier: Genscript

SARS-CoV-2 (Severe acute respiratory syndrome coronavirus 2) is a positive-sense single-stranded RNA virus. It caused coronavirus disease 2019 (COVID-19). The B.1.1.529 variant was first reported to WHO from South Africa on 24 November 2021. WHO has designated B.1.1.529 as a VOC, named Omicron. SARS-CoV-2 contains glycosylated spike (S) protein, which is composed of S1 subunit and S2 subunit. The S1 contains a receptor-binding domain (RBD) that can bind to ACE2 receptor on target cells. Neutralizing antibodies against SARS-CoV-2 can block the interaction between SARS-CoV-2 RBD and ACE2. The blocking ability of SARS-CoV-2 neutralizing antibodies is affected by the quantity.This standard product is intended for the calibration of SARS-CoV-2 Omicron neutralizing antibodies. It can be used in the assessment and development of assays for the detection and quantitation of SARS-CoV-2 Omicron neutralizing antibodies. The neutralizing antibody standard binds to multiple neutralizing epitopes in the receptor-binding domain.

Supplier: Genscript

GenScript Streptavidin Antibody is specific to streptavidin.

Supplier: Genscript

THE™ c-Myc Tag antibody, mAb, Mouse recognizes C-terminal, N-terminal and internal c-Myc tagged fusion proteins expressed in prokaryotic or eukaryotic cells. It also recognizes c-Myc protein in human cancers or cell lines such as Hela cell lysates.

Supplier: Genscript

THE™ DYKDDDDK Tag antibody, mAb, Mouse recognizes DYKDDDDK; tags localized at the C-terminal, N-terminal and internal region of DYKDDDDK
tagged fusion proteins.

Supplier: Genscript

The product is specific for Rituximab. The antibody is recommended as a capture antibody in a pharmacokinetic (PK) bridging assay with detection antibody GenScript, A01944-40, MonoRab™ Anti-Rituximab Antibody (194D7) [Biotin], mAb, Rabbit.

Supplier: Genscript

The product is specific for Cetuximab. This antibody can’t block Cetuximab binding with EGFR (Z03202, EGFR, His, Human) in ELISA. The antibody is recommended as a capture antibody in a pharmacokinetic (PK) bridging assay with detection antibody GenScript, A01938-40, Anti-Cetuximab Antibody (18D5), mAb, Mouse.

Supplier: Genscript

The product is specific for Nivolumab. The antibody is recommended as a detection antibody in a pharmacokinetic (PK) bridging assay with capture antibody GenScript, A01847-40, Anti- Nivolumab Antibody (8G6G3D8), mAb, Mouse.

Supplier: Genscript

The product is specific for daratumumab.