279 Results for: "CUBE BIOTECH"
PureCube HIC Starter Set (Butyl, Phenyl, Octyl Agarose)
Supplier: CUBE BIOTECH
The PureCube HIC starter set includes 10 ml of each of the following HIC resins: PureCube butyl agarose, PureCube phenyl agarose, and PureCube octyl agarose.
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Mouse Recombinant MSP1D1 (from E. coli)
Supplier: CUBE BIOTECH
Membrane scaffold protein, mouse origin.
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Mouse Recombinant MSP2N2 (from E. coli)
Supplier: CUBE BIOTECH
Membrane scaffold protein, mouse origin.
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FOCUS: SAFETY - OUT NOW!
Let’s enhance safety by considering personalized protection equipment (PPE) solutions tailored to your team, processes, and products.
PureCube Fe-NTA MagBeads
Supplier: CUBE BIOTECH
PureCube Fe-NTA MagBeads were developed to enrich phosphorylated proteins. They can also be used to purify His-tagged proteins as a secondary function.
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HiYield-T7 Cell-free E. coli Lysate
Supplier: CUBE BIOTECH
Our E. coli cell-free lysates are the isolated protein purification machinery of bacterial cells. They create a high-yielding and adjustable cell-free protein expression system.
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PureCube Alprenolol Agarose
Supplier: CUBE BIOTECH
PureCube Alprenolol resin provides highly-specific purification β-adrenergic receptors with maximum protein yield.
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PureCube Epoxy Activated Agarose XL
Supplier: CUBE BIOTECH
PureCube epoxy agarose XL resin is your best option to couple biomolecules that carry thiol (SH) groups.
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PureCube Amine Activated Agarose XL
Supplier: CUBE BIOTECH
PureCube amine activated agarose XL resin is your best option to couple biomolecules carrying free-standing carboxy (COOH) groups.
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AASTY 6-50
Supplier: CUBE BIOTECH
AASTYs (Acrylic acid-co-styrenes) - like AASTY 6-50 - are highly-alternating copolymers, well-suited for the generation of native lipid nanodiscs. They are a 2022 novel developed series for membrane protein solubilization & stabilization. AASTY 6-50 gets its name from its molecular weight and Acrylic Acid : Styrene Ratio. These varying ratios of acrylic acid to styrene contribute to the hydrophilic properties of our AASTYs. In general lighter AASTYs, like 6-50 tend to be more aggressive, while heavier AASTYs, such as 11-45 show higher thermodynamic stability.
The exact composition of AASTY copolymers shows different extraction efficiency, depending on the lipid composition of the lipid bilayers being formulated into nanodiscs. As AASTY is made using controlled radical polymerization techniques, the dispersity of polymer molecular weight distribution is low, and the molecular weights are controlled. This means that excess AASTY copolymer can be removed by dialysis after nanodisc formation. Based on previous findings on SMA, it is the expectation that AASTY of different molecular weights will display different rates of nanodisc formation, extraction efficacy, and stability of resulting nanodiscs.
Every membrane protein solubilization needs to undergo a screening process before. The characteristic phospholipid environment surrounding the different membrane proteins in question performs differently well with each polymer. To support you in this process we offer a handy Screening Kit for AASTYs to test them all. Additionally, we recommend the two following publications if you would like to get further information: Smith et al. 2020 & Timcenko et al. 2022
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AASTY 11-50
Supplier: CUBE BIOTECH
AASTYs (Acrylic acid-co-styrenes) - like AASTY 11-50 - are highly-alternating copolymers, well-suited for the generation of native lipid nanodiscs. They are a 2022 novel developed series for membrane protein solubilization & stabilization. AASTY 11-50 gets its name from its molecular weight and Acrylic Acid : Styrene Ratio. These varying ratios of acrylic acid to styrene contribute to the hydrophilic properties of our AASTYs. In general lighter AASTYs, like 6-45 tend to be more aggressive, while heavier AASTYs, such as 11-50 show higher thermodynamic stability.
Every membrane protein solubilization needs to undergo a screening process in before. The characteristic phospholipid environment surrounding the different membrane proteins in question performs differently well with each polymer. To support you in this process, we offer a handy Screening Kit for AASTYs to test them all.
We recommend the two following publications if you would like to get further information: Smith et al. 2020 & Timcenko et al. 2022
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FPLC Column/Cartridge Assembly Press
Supplier: CUBE BIOTECH
The FPLC Cartridge assembly press is an efficient tool that simplifies the packaging process for FPLC columns.
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Decyl-β-D-glucopyranoside ≥99.5%, Crystallization grade
Supplier: CUBE BIOTECH
Mild, non-ionic detergents such as Decylglucoside are well suited for the solubilization, stabilization, and purification of membrane proteins. For screening of the best-suited detergent for a given application, we offer glucosides with chain lengths from C-8 to C-10, as well as octylthioglucoside.
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PureCube Maleimide Activated MagBeads
Supplier: CUBE BIOTECH
PureCube Maleimide MagBeads are your best option to couple biomolecules that carry thiol (SH) groups.
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SARS-CoV-2 Recombinant SARS CoV-2 Spike Protein in LMNG Detergent (from HEK293 cells)
Supplier: CUBE BIOTECH
The coronavirus, also known as SARS-CoV-2, enters the cell by using its surface SPIKE. SPIKE is processed on the cell's surface by TMPRSS2, a serine protease. It then subsequently binds to ACE2 a cell surface receptor.
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PureCube NTA XL Agarose
Supplier: CUBE BIOTECH
PureCube NTA XL (nitrilotriacetic acid) agarose resin was developed for IMAC-based protein purification and protein enrichment methods.
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PureCube Amine Activated Agarose
Supplier: CUBE BIOTECH
PureCube amine activated agarose resin is your best option to couple biomolecules carrying free-standing carboxy (COOH) groups.
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PureCube Carboxy MagBeads
Supplier: CUBE BIOTECH
PureCube amine carboxy agarose MagBeads are your best option to couple biomolecules that carry free-standing Amine (NH₂) groups.
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PureCube Epoxy Activated MagBeads
Supplier: CUBE BIOTECH
PureCube epoxy activated MagBeads are your best option to couple biomolecules that carry free-standing amine (NH₂) and thiol (SH) groups.
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PureCube Ni-IDA MagBeads
Supplier: CUBE BIOTECH
PureCube Ni-IDA MagBeads were developed by Cube Biotech for His-tag protein purification.
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Nanodisc MSP2N2-His DMPC
Supplier: CUBE BIOTECH
This product is a pre-assembled nanodisc. Its intended purpose is to stabilize a cell-free expressed membrane protein.
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Nanodisc Rat MSP1E3D1-His DMPC
Supplier: CUBE BIOTECH
Membrane scaffold protein; rat origin.
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PureCube Compact Cartridge NTA
Supplier: CUBE BIOTECH
The PureCube NTA (nitrilotriacetic acid) Compact Cartridge was developed for IMAC-based protein purification and protein enrichment methods.
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HisCube HisCube Ni-Indigo MagBead Protein Purification MINI Kit
Supplier: CUBE BIOTECH
The HisCube MagBead protein purification MINI kit is designed to meet the demands of your laboratory for efficient and high-quality small-scale His-tag protein purifications.
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AASTY 11-45
Supplier: CUBE BIOTECH
AASTYs (Acrylic acid-co-styrenes) - like AASTY 11-45 - are highly alternating copolymers, well-suited for the generation of native lipid nanodiscs. They are a 2022 novel developed series for membrane protein solubilization & stabilization. AASTY 11-45 gets its name from its molecular weight and Acrylic Acid : Styrene Ratio. These varying ratios of acrylic acid to styrene contribute to the hydrophilic properties of our AASTYs. In general lighter AASTYs, like 6-45 tend to be more aggressive, while heavier AASTYs, such as 11-45 show higher thermodynamic stability.
The exact composition of AASTY copolymers shows different extraction efficiency, depending on the lipid composition of the lipid bilayers being formulated into nanodiscs. As AASTY is made by controlled radical polymerization techniques, the dispersity of polymer molecular weight distribution is low, and the molecular weights are controlled. This means that excess AASTY copolymer can be removed by dialysis after nanodisc formation. Based on previous findings on SMA, it is the expectation that AASTY of different molecular weights will display different rates of nanodisc formation, extraction efficacy, and stability of resulting nanodiscs.
Every membrane protein solubilization needs to undergo a screening process before. The characteristic phospholipid environment surrounding the different membrane proteins in question performs differently well with each polymer. To support you in this process, we offer a handy Screening Kit for AASTYs to test them all. Additionally, we recommend the two following publications if you would like to get further information: Smith et al. 2020 & Timcenko et al. 2022
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Nanodisc Assembly Kit MSP1D1 dH5-His POPC
Supplier: CUBE BIOTECH
This product is a MSP nanodisc assembly kit. It contains a vial of lyophilized membrane scaffold protein MSP1D1 dh5 (His-tagged) and a vial of DMPC or POPC phopshospholipid to assemble a MSP nanodisc.
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Human Recombinant MSP2N2 (from E. coli)
Supplier: CUBE BIOTECH
Membrane scaffold protein, human origin.
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Nanodisc MSP1D1 dH5-His POPC Biotinyl PE
Supplier: CUBE BIOTECH
This product is a pre-assembled nanodisc. Its intended purpose is to stabilize a cell-free expressed membrane protein.
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Nanodisc Assembly Kit MSP1D1 dH5-His DMPC
Supplier: CUBE BIOTECH
This product is a MSP nanodisc assembly kit. It contains a vial of lyophilized membrane scaffold protein MSP1D1 dh5 (His-tagged) and a vial of DMPC or POPC phopshospholipid to assemble a MSP nanodisc.
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n-Tridecyl-β-D-maltoside ≥99.5%, Crystallization grade
Supplier: CUBE BIOTECH
Mild, non-ionic detergents such as Tridecylmaltoside are well suited for the solubilization, stabilization, and purification of membrane proteins. For screening of the best-suited detergent for a given application, we offer maltosides with chain lengths from C-9 to C-13.
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HiYield Cell-free E. coli Lysate
Supplier: CUBE BIOTECH
Our E. coli cell-free lysates are the isolated protein purification machinery of bacterial cells. They create a high-yielding and adjustable cell-free protein expression system.