3087 Results for: "Bachem Americas"

Supplier: Bachem Americas

Exendin-3, a member of the glucagon superfamily, was originally isolated from the venom of the lizard, Heloderma horridum. At low concentrations, the 39-amino acid peptide interacts with putative exendin receptors causing an increase in pancreatic acinar cAMP, whereas at higher concentrations it interacts with VIP receptors to stimulate an increase in cellular cAMP and amylase release.

Supplier: Bachem Americas

Exendin (9-39) is a potent glucagon-like peptide 1 (GLP-1) receptor antagonist. It has also been described as an antagonist of the putative exendin receptor. Exendin (9-39) blocks the stimulatory action of GLP-1 (7- 36) amide (H- 6795) and of exendin-4 (H- 8730) on cAMP production in pancreatic acini. Moreover, exendin (9-39) was shown to be safely used to abolish the incretin effect of GLP-1 without interfering with the control of insulin secretion by circulating nutrients.

Supplier: Bachem Americas

See also the pTH2 receptor agonist TIP39 (H-4878).

Supplier: Bachem Americas

This C-terminal fragment of NPY is a more potent inhibitor of calmodulin-stimulated phosphodiesterase than NPY itself. The inhibitory effect obviously depends on the basic amphiphilic helical nature of the fragment.

Supplier: Bachem Americas

1G CAS: 281670-51-7 C9H16N2O4 · HCl FW: 252.7

Supplier: Bachem Americas

Please see also 5-(Pentafluorobenzoylamino)fluorescein (M-2375), a sensitive fluorogenic substrate for the determination of glutathione S-transferase (GST) activity and glutathione (GSH) concentration, and the carba-analog of GSH, ophthalmic acid, H-3145.

Supplier: Bachem Americas

Also known as dioxopiperazines, piperazine-2,5-diones or DKPs. Diketopiperazines may occur as by-products during peptide synthesis or during the degradation of peptides. These cyclic dipeptides have been detected as taste-modulating compounds in food, they often show biological activity. DKPs are valuable chiral synthons, employed e.g. in Schöllkopf's versatile bislactim ether approach. They also have found use as catalysts for enantioselective synthesis, e.g. in the asymmetric Strecker reaction. See also the TRH metabolite cyclo(-His-Pro), G-1745, and cyclo(-Asp-Phe), G-1695, the major degradation product of aspartame.

Supplier: Bachem Americas

5mg CAS: 10466-28-1 C77H108N20O20S FW: 1665.89 . Synonym: Acetyl-ACTH (1-13)

Supplier: Bachem Americas

Please see also α-MSH (corresponds to acetyl-ACTH (1-13) amide, H-1075), α-MSH (free acid) (acetyl-ACTH (1-13), H-1070), and (Des-acetyl)-α-MSH (H-4390). Wied: Pituitary Adrenal System Hormones and Behaviour. Symposium on Developments in Endocrinology (1976) / Anon.: ACTH and Related Peptides: Structure, Regulation, and Action. Ann. N.Y. Acad. Sci. 297, 1 (1977) / A.V.Schally: Aspects of Hypothalamic Regulation of the Pituitary Gland. Science 202, 18 (1978) / R.Schwyzer: Studies on Polypeptide Receptors. A Critical View on the Mechanism of ACTH Action. Bull. Schweiz. Acad. Med. Wiss. 34, 263 (1978).

Supplier: Bachem Americas

Sequence: H-Arg(Pmc)-OtBu (free base)

Supplier: Bachem Americas

Sequence: H-Glu-OtBu

Supplier: Bachem Americas

Sequence: Dde-Lys(Fmoc)-OH

Supplier: Bachem Americas

Sequence: H-Glu(OMe)-NH₂ · HCl

Supplier: Bachem Americas

Sequence: Ac-Asn-OH

Supplier: Bachem Americas

Antimicrobial peptides are produced by plants and most organisms throughout the animal kingdom including humans. Antimicrobial peptides protect against a broad range of infectious agents, as bacteria, fungi, and viruses. The amphibian skin is an especially rich source of antimicrobial peptides. See also the product families: Hepcidins LL-37 and Fragments Tuftsin and Analogs (subfamily).

Supplier: Bachem Americas

Besides deltorphins, dermorphins, dynorphins, enkephalins and endorphins, Bachem offers opioid peptides such as acetalins, BAM peptides, α-casein and gluten exorphins, endomorphins, kyotorphins, metorphamide, opiorphins, δ opioid receptor antagonists, and valorphin.

Supplier: Bachem Americas

The octapeptide RFYVVMWK constitutes the active sequence within the 30-mer peptide named C₄ as it is essential for the cell attachment activity of the TS1 CBD. It supports the attachment of G361 melanoma cells and inhibits their adhesion to the rec CBD of TS1. Moreover, this peptide appears to be highly conserved in all TS1 isoforms, and a related sequence is also present in the fragment F9 of laminin. H-1414 (4N1) has been used as CD47 agonist (see also H-6414).

Supplier: Bachem Americas

Sequence: 3-Palmitoyl-sn-glycerol
Synonym(s): L-α-Palmitin

Supplier: Bachem Americas

Sequence: 1,2-Dilauroyl-sn-glycero-3-phosphocholine
Synonym(s): DLPC#L-β,γ-Dilauroyl-α-lecithin

Supplier: Bachem Americas

Sequence: 1,3-Dipalmitoyl-glycerol
Synonym(s): α,γ-Dipalmitin

Supplier: Bachem Americas

Sequence: 1,2-Distearoyl-sn-glycero-3-phosphocholine
Synonym(s): DSPC#L-β,γ-Distearoyl-α-lecithin

Supplier: Bachem Americas

Sequence: 1,2-Dipalmitoyl-sn-glycero-3-phosphocholine
Synonym(s): DPPC#L-β,γ-Dipalmitoyl-α-lecithin

Supplier: Bachem Americas

Sequence: 1-O-Hexadecyl-sn-glycero-3-phosphocholine

Supplier: Bachem Americas

Sequence: 1,2-Dimyristoyl-sn-glycerol
Synonym(s): D-α,β-Dimyristin

Supplier: Bachem Americas

Sequence: 1,2-O-Dioctadecyl-sn-glycerol
Synonym(s): D-α,β-Dioctadecyl-glycerol

Supplier: Bachem Americas

Sequence: 1-Methyl-1H-imidazole-2-carboxylic acid

Supplier: Bachem Americas

Sequence: 3-Methoxytyramine · HCl
Synonym(s): 3-MT · HCl#3-O-Methyldopamine · HCl

Supplier: Bachem Americas

Sequence: Ac-muramic acid
Synonym(s): MurNAc#NAMA

Supplier: Bachem Americas

Sequence: Ac-α-benzyl-4,6-O-benzylidene-muramic acid

Supplier: Bachem Americas

Sequence: 7-Amino-4-methylcoumarin
Synonym(s): AMC