3087 Results for: "Bachem Americas"

Supplier: Bachem Americas

Sequence: H-Homoarg-OH

Supplier: Bachem Americas

Sequence: H-D-Dap-OH · HCl

Supplier: Bachem Americas

Sequence: H-D-Val-OMe · HCl

Supplier: Bachem Americas

Sequence: H-β-(3-Pyridyl)-Ala-OH
Synonym(s): H-3-Pal-OH#(S)-2-Amino-3-pyridin-3-yl-propionic acid#C³-(3-Pyridyl)-L-alanine

Supplier: Bachem Americas

Sequence: H-D-His(3-Me)-OH

Supplier: Bachem Americas

Sequence: H-DL-δ-Hydroxy-DL-Lys-OH · HCl

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Sequence: H-Hyp-OH

Supplier: Bachem Americas

PAR peptides (TRAP peptides and thrombin receptor-like peptides) activate the proteinase-activated receptors PAR-1 to PAR-4.

Supplier: Bachem Americas

Sequence: Fmoc-L-cysteic acid · disodium salt
Synonym(s): Fmoc-Cya-OH · disodium salt

Supplier: Bachem Americas

Sequence: Fmoc-Dab(ivDde)-OH

Supplier: Bachem Americas

Sequence: Fmoc-D-Trp(Me)-OH

Supplier: Bachem Americas

Sequence: Fmoc-Dap(ivDde)-OH

Supplier: Bachem Americas

These dipeptide building blocks containing Ser- or Thr-derived oxazolidines (pseudoprolines) proved to be versatile tools for overcoming some intrinsic problems in the field of peptide chemistry. The presence of pseudoprolines within a peptide sequence results in the disruption of β-sheet structures considered as a source of intermolecular aggregation during chain elongation, thus increasing solvation and coupling kinetics in peptide assembly. Therefore, use of pseudoprolines offer new possibilities for accessing large peptides by convergent strategies and chemoselective ligation techniques. Moreover, incorporation of a pseudoproline unit facilitates cyclization of peptides.

Supplier: Bachem Americas

These dipeptide building blocks containing Ser- or Thr-derived oxazolidines (pseudoprolines) proved to be versatile tools for overcoming some intrinsic problems in the field of peptide chemistry. The presence of pseudoprolines within a peptide sequence results in the disruption of β-sheet structures considered as a source of intermolecular aggregation during chain elongation, thus increasing solvation and coupling kinetics in peptide assembly. Therefore, use of pseudoprolines offer new possibilities for accessing large peptides by convergent strategies and chemoselective ligation techniques. Moreover, incorporation of a pseudoproline unit facilitates cyclization of peptides.

Supplier: Bachem Americas

Sequence: Fmoc-N-Me-Tyr(tBu)-OH

Supplier: Bachem Americas

This monocyte-macrophage-derived cytokine was first characterized by its in vivo antitumor properties and in vitro cytotoxicity to certain transformed cell lines. TNF-α also exerts a growth-enhancing effect on various cells and thus is a bifunctional growth regulator like e.g. IFN-α. As a mediator of inflammatory processes, TNF-α shares many similar biological activities with IL-1.

Supplier: Bachem Americas

In search of competitive α-MSH antagonists, the hexapeptide GHRP-6 has been recognized as a selective inhibitor of α-MSH activity in the frog skin bioassay. It is identical in sequence with a growth hormone-releasing peptide analog, (His¹,Lys⁶)-GHRP, which selectively releases GH in vitro and in a wide variety of species in vivo. GHRP-6 also acts as a functional antagonist of somatostatin in the somatotrope cells.

Supplier: Bachem Americas

Antimicrobial peptides are produced by plants and most organisms throughout the animal kingdom including humans. Antimicrobial peptides protect against a broad range of infectious agents, as bacteria, fungi, and viruses. The amphibian skin is an especially rich source of antimicrobial peptides. See also the product families: Hepcidins LL-37 and Fragments Tuftsin and Analogs (subfamily).

Supplier: Bachem Americas

Antimicrobial peptides are produced by plants and most organisms throughout the animal kingdom including humans. Antimicrobial peptides protect against a broad range of infectious agents, as bacteria, fungi, and viruses. The amphibian skin is an especially rich source of antimicrobial peptides. See also the product families: Hepcidins LL-37 and Fragments Tuftsin and Analogs (subfamily).

Supplier: Bachem Americas

The investigation of the adjuvant activity of this muramyl peptide on humoral and cellular immune responses showed that it augments the mitogenic responses of splenic lymphocytes to phytohemagglutinin and lipopolysaccharide and the formation of antibodies to sheep erythrocytes in mice. In addition, it potentiated polyclonal B cell activation in vivo and in vitro.

Supplier: Bachem Americas

pTHrP (1-86) increased bone formation in vitro.

Supplier: Bachem Americas

See also the product families 'Adjuvant Peptides' and 'Thymosins and Fragments'.

Supplier: Bachem Americas

GPG-NH2 was shown to inhibit the replication of HIV-1 via its metabolite α-hydroxyglycineamide. The tripeptide added to the antiviral effect of both zidovudine and ritonavir.
Sequence: H-Gly-Pro-Gly-NH2 · HCl
CAS Number: 141497-12-3
Molecular Formula: C9H16N4O3 · HCl
Molecular Weight: 264.71

Supplier: Bachem Americas

250mg CAS: 51790-14-8 C17H24N4O3 FW: 332.4

Supplier: Bachem Americas

1G CAS: 32949-40-9 C10H18N2O5 FW: 246.26

Supplier: Bachem Americas

Please see also 5-(Pentafluorobenzoylamino)fluorescein (M-2375), a sensitive fluorogenic substrate for the determination of glutathione S-transferase (GST) activity and glutathione (GSH) concentration, and the carba-analog of GSH, ophthalmic acid, H-3145.

Supplier: Bachem Americas

(Des-Gly)-Ophthalmic acid

Supplier: Bachem Americas

Like L-carnosine (G-1250), L-anserine is a histidine-containing dipeptide found in vertebrate skeletal muscles. Both are potent antioxidants with membrane-stabilizing function.

Supplier: Bachem Americas

The dipeptide His-Pro-amide represents the initial enzymatic degradation product of TRH in plasma. CAS Number (net): 33605-69-5.

Supplier: Bachem Americas

Inhibitor of carboxypeptidase U (thrombin activatable fibrinolysis inhibitor, TAFI), Ki 0.14 μM.