3087 Results for: "Bachem Americas"

Supplier: Bachem Americas

Educt (coupled to Wang resin) for obtaining a library of p-biphenylalanines via Suzuki coupling.

Supplier: Bachem Americas

Please see also α-MSH (corresponds to acetyl-ACTH (1-13) amide, H-1075), α-MSH (free acid) (acetyl-ACTH (1-13), H-1070), and (Des-acetyl)-α-MSH (H-4390). Wied: Pituitary Adrenal System Hormones and Behaviour. Symposium on Developments in Endocrinology (1976) / Anon.: ACTH and Related Peptides: Structure, Regulation, and Action. Ann. N.Y. Acad. Sci. 297, 1 (1977) / A.V.Schally: Aspects of Hypothalamic Regulation of the Pituitary Gland. Science 202, 18 (1978) / R.Schwyzer: Studies on Polypeptide Receptors. A Critical View on the Mechanism of ACTH Action. Bull. Schweiz. Acad. Med. Wiss. 34, 263 (1978).

Supplier: Bachem Americas

Protected derivative of L-azidohomoalanine (Aha), a Met isostere. This building block for 'click chemistry' additionally creates a specific cleavage site in peptides, Aha-containing sequences can be cleaved under mild conditions in the presence of phosphines or dithiols via formation of homoserine lactone.

Supplier: Bachem Americas

The protein dermcidin expressed in the sweat glands is secreted into the sweat and transported to the epidermal surface. The concomitant processing of the protein yields a broad-spectrum antimicrobial 47 amino acid peptide, dermcidin-1 (DCD-1).

Supplier: Bachem Americas

LL-37 H-Leu-Leu-Gly-Asp-Phe-Phe-Arg-Lys-Ser-Lys-Glu-Lys-Ile-Gly-Lys-Glu-Phe-Lys-Arg-Ile-Val-Gln-Arg-Ile-Lys-Asp-Phe-Leu-Arg-Asn-Leu-Val-Pro-Arg-Thr-Glu-Ser-OH Trifluoroacetate salt 5mg, Antibacterial Protein LL-37 (human), LL37, CAMP, C205H340N60O53, Cas 154947-66-7.

Supplier: Bachem Americas

LHRH is also called Gonadotropin-Releasing Hormone (GnRH) or Luteinizing Hormone-Releasing Factor (LRF).

Supplier: Bachem Americas

CALP-3, VKFGVGFK, acts as a calmodulin agonist. The octapeptide interacts with the calmodulin EF-hand motif, the Ca²⁺-binding site. CALP-3 activates phosphodiesterase in the absence of calcium and inhibits Ca²⁺-mediated cytotoxicity and apoptosis. CALP-3 is more active than CALP-1 (H-8155), By preventing trypsin activation within pancreatiic acinar cells CALP-3 shows potential therapeutic potential in the treatment of pancreatitis.

Supplier: Bachem Americas

Substitution 0.50-0.90 mmol/g Storage Conditions -20 +/- 5 Deg C 1g

Supplier: Bachem Americas

These dipeptide building blocks containing Ser- or Thr-derived oxazolidines (pseudoprolines) proved to be versatile tools for overcoming some intrinsic problems in the field of peptide chemistry. The presence of pseudoprolines within a peptide sequence results in the disruption of β-sheet structures considered as a source of intermolecular aggregation during chain elongation, thus increasing solvation and coupling kinetics in peptide assembly. Therefore, use of pseudoprolines offer new possibilities for accessing large peptides by convergent strategies and chemoselective ligation techniques. Moreover, incorporation of a pseudoproline unit facilitates cyclization of peptides.

Supplier: Bachem Americas

Dodecyl pentaethylene glycolether
CAS: 3055-95-6
Formula: C22H46O6
M.W: 406.6
Storage temp.: -20 ± 5 °C

Supplier: Bachem Americas

Octyl glucoside
CAS: 29836-26-8
Formula: C14H28O6
M.W: 292.37
Storage temp.: -20 ± 5 °C

Supplier: Bachem Americas

Desmopressin (DDAVP), as the first vasopressin analog with a very high and very specific antidiuretic effect, has been widely used for different therapeutic purposes. DDAVP also improves human learning and memory processes. CAS Number (desmopressin acetate): 62288-83-9.

Supplier: Bachem Americas

MEGA-10
CAS: 85261-20-7
Formula: C17H35NO6
M.W: 349.47
Storage temp.: -20 ± 5 °C

Supplier: Bachem Americas

An RGD tumor-targeting peptide, which binds to αvβ3 receptors. c(RGDfK) can be easily conjugated to fluorophore tags, chelators, or carriers. Palecek et al. converted the ε-amino group into the azide by diazo transfer allowing further functionalization by click chemistry. Mercapto groups can be introduced via acylation of c(RGDfK) with S-acetylthioacetic acid (SATA).

Supplier: Bachem Americas

Amyloid beta Protein (1-40) Trifluoroacetate salt, Formula: C194H295N53O58S, CAS: 131438-79-4, It showed both neurotrophic and neurotoxic effects in dependence on the neuronal age and the concentration of the beta -protein. Used to detect multimers in the cerebrospinal fluid

Supplier: Bachem Americas

Besides a large selection of tyrosine derivatives, Bachem offers derivatives of O-alkylated tyrosines, thyronine, phosphotyrosine and sulfotyrosine.Bachem additionally offers H-[¹⁵N]Tyr-OH, E-3245.

Supplier: Bachem Americas

Sequence: H-Cys(4-methoxytrityl)-2-chlorotrityl resin (200-400 mesh)
Synonym(s): H-Cys(Mmt)-2-ClTrt resin

Supplier: Bachem Americas

LHRH is also called Gonadotropin-Releasing Hormone (GnRH) or Luteinizing Hormone-Releasing Factor (LRF).

Supplier: Bachem Americas

Sequence: ((RS)-2-Benzyl-3-mercaptopropionyl)-Gly-OH

Supplier: Bachem Americas

Besides deltorphins, dermorphins, dynorphins, enkephalins and endorphins, Bachem offers opioid peptides such as acetalins, BAM peptides, α-casein and gluten exorphins, endomorphins, kyotorphins, metorphamide, opiorphins, δ opioid receptor antagonists, and valorphin.

Supplier: Bachem Americas

The dipeptides H-Ala-Gln-OH and H-Gly-Gln-OH (N-1070) are stable substitutes for Gln in cell culture media, which tolerate autoclaving and liberate a lower amount of undesired ammonia than Gln. Ala-Gln and Gly-Gln have also found use as Gln sources in parenteral nutrition.

Supplier: Bachem Americas

See also the pTH2 receptor agonist TIP39 (H-4878).

Supplier: Bachem Americas

Ramage resin is highly suitable for the preparation of peptide amides by the Fmoc-strategy and is recommended for C-terminal Phe, Tyr and Ile. Cleavage has been performed with 50 % TFA in CH₂Cl₂ or 95% aqueous TFA. Scavengers may be required. Tricyclic amide linker resin has been used for the synthesis of fluorogenic substrates for continuous assay of aminopeptidase P. Bachem additionally offers the Ramage amide linker (Q-2745) to be coupled to other types of carrier resin.

Supplier: Bachem Americas

Sequence: Z-Val-Ala-Asp-AMC
Synonym(s): Z-VAD-AMC

Supplier: Bachem Americas

Sequence: Ac-Tyr-Val-Ala-Asp-AFC
Synonym(s): Ac-YVAD-AFC

Supplier: Bachem Americas

Substrate for the determination of a new cysteine endopeptidase which is required for antigen processing. Z-VAN-AMC has been used as a fluorogenic substrate for porcine asparaginyl endopeptidase (AEP, legumain).

Supplier: Bachem Americas

Ac-YVAD-AMC is a fluorogenic substrate for caspase-1 (ICE). It displayed a Km of 8.5 ± 0.5 µM for recombinant human caspase-1.

Supplier: Bachem Americas

Substrates for measuring the chymotryptic, PGPH, and tryptic acitivity of the 20S or 26S proteasome. See also the thrombin substrate I-1140.

Supplier: Bachem Americas

Substrates for measuring the chymotryptic, PGPH, and tryptic acitivity of the 20S or 26S proteasome. See also the thrombin substrate I-1140.

Supplier: Bachem Americas

Sequence: Ac-Arg-Gly-Lys(Ac)-AMC
Synonym(s): Ac-RGK(Ac)-AMC