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Spécifications
- Animal-free:Y
- Protease-free:Y
- Protein Function:Cytokine
- Protein/peptide type:Recombinant
- Source:E. coli
- Species:Mouse
- Size:5 μg
- Storage conditions:Store at –20 °C prior to opening
- Endotoxin content:≤ 1.00 EUs/μg
- Biological activity:Induce IL-6 production from M1 cells at less than or equal to 1 ng/mL or (1 x 10^6 units/mg specific units)
- Reconstitution instructions:Reconstitute with Sterile 10 mM acetic acid at 0.1 mg/mL
- Protein synonyms:Leukocyte Inhibitory Factor
- UniProtKB:P09056
- Protein/peptide name:LIF
- Purity:>95%
- Molecular weight:20.0 (kDa) Monomer
- Sequence:MSPLPITPVN ATCAIRHPCH GNLMNQIKNQ LAQLNGSANA LFISYYTAQG EPFPNNVEKL CAPNMTDFPS FHGNGTEKTK LVELYRMVAY LSASLTNITR DQKVLNPTAV SLQVKLNATI DVMRGLLSNV LCRLCNKYRV GHVDVPPVPD HSDKEAFQRK KLGCQLLGTY KQVISVVVQA F
- Endotoxin level:Low
- Formulation:Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 0.1% Trifluoroacetic Acid (TFA)
- Shipping temperature:Ambient
- Cat. no.:10788-080
- Origin:USA
- Supplier No.:200-33AF-5UG
Spécifications
A propos de cet article
Mouse leukemia inhibitory factor (LIF) is a member of the interleukin 6 (IL-6) family that is made by a variety of adult and embryonic tissues. LIF signals through the glycoprotein 130 (gp130)/LIF receptor (LIFR) heterodimer to activate STAT3 and MAPK signaling. LIF functions during hematopoietic differentiation, neuronal cell differentiation, kidney development, and inflammatory processes. The application of mouse LIF to long-term culture systems promotes mouse embryonic stem (ES) cell self-renewal and pluripotency, similar to the functional activity of bFGF (FGF2) in human ES cell culture systems.
- Animal-free
Shenandoah Biotechnology is a manufacturer of research grade recombinant proteins typically used as cytokines, growth factors and chemokines in cell based assays and cell culture. Each production lot is tested for QA and the expected values for each product can be viewed under the product specifications tab.
A COA is supplied with each product shipped detailing purity, formulation, biological activity, endotoxin levels, reconstitution instructions and recommended storage conditions. This product is for research use only and is not for use in humans.