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Specifications
- Conjugation:Unconjugated
- Protein Function:Cytokines and Growth Factors
- Protein/peptide type:Recombinant
- Source:E. coli
- Species:Human
- Size:5 μg
- Protein/peptide name:CNTF
- Protein synonyms:Ciliary Neurotrophic Factor
- Gene ID:1270 P26441
- Sequence:AFTEHSPLTP HRRDLCSRSI WLARKIRSDL TALTQSYVKH QGLNKNINLD SADGMPVAST DQWSQLTQAQ RLQQNLQAYR TFHVLLARLL QDQQVHFTPT QGDFHQAIHT LLLQVAAFAY QIQQLMILLQ YKIPRNQADG MPINVGDGGL FQKKLWGLKV LQQLSQWTVR SIHDLRFISS HQTGIPARGS HYIANNKKM
- Endotoxin content:>0.1 ng/μg
- Biological activity:Biological Activity tests can vary. Please refer to the Product CoA for information.
- Protease-free:Y
- Purity:0.98
- Form:Lyophilized
- Formulation:Formulation can vary. Please refer to product CoA for information.
- Molecular weight:22.8 kDa
- Reconstitution instructions:Reconstitution instructions can vary. Please refer to the product CoA for info.
- Storage conditions:Store at –20 °C prior to reconstitution.
- Shipping temperature:Ambient
- Endotoxin level:Low
- Cat. no.:10781-256
- Origin:USA
- Supplier No.:450-13-5UG
Specifications
About this item
CNTF is a potent neural factor that was originally characterized as a vital factor for the survival of chick ciliary neurons in vitro . CNTF is also important for the survival of other neural cell types, including primary sensory neurons, motor neurons, basal forebrain neurons and type 2 astrocytes. CNTF is highly conserved across species and exhibits cross-species bioactivity. Recombinant Human CNTF is synthesized as a 199 amino acid polypeptide (22.8 kDa) lacking a hydrophobic N-terminal signal for secretion.