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Spécifications
- Antibody type:Primary
- Antigen name:Multidrug Resistance-associated Protein 4
- Clonality:Monoclonal
- Clone:M4I-10
- Gene ID:10257
- Host:Rat
- Isotype:IgG2a
- Reactivity:Human
- Antigen symbol:MRP4
- Conjugation:Unconjugated
- Flow cytometry:Yes
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Size:500 μl
- Western blot:Yes
- Antigen synonyms:MOAT-B|ATP-binding cassette sub-family C member 4|MRP/cMOAT-related ABC transporter|multi-specific organic anion transporter B|member 4)|MOATB|sub-family C (CFTR/MRP)|EST170205|MRP4|RP11-74A12.1|multispecific organic anion transporter B|bA464I2.1 (ATP-binding cassette|multidrug resistance-associated protein 4|canalicular multispecific organic anion transporter (ABC superfamily)
- Storage buffer:Preservative: 0.1% Sodium Azide; Constituents: 0.7% BSA, Tissue culture supernatant
- Storage temperature:Keep as concentrated solution. Store at 4 °C short term. For extended storage aliquot and store at –20 °C or below. Avoid freeze-thaw cycles.
- Concentration:0.15 mg/ml
- Immunogen:This antibody was selected after immunization with a fusion protein containing the E. coli maltose binding protein and a fragment of the human MRP4 protein corresponding to amino acids 372-431.
- Tested applications:Fluorescence-Activated Cell Sorting
- Purification:Tissue culture supernatant
- Cat. no.:89367-424
- Supplier No.:GTX15602
Spécifications
A propos de cet article
MRP4 transports cyclic nucleotides and anti-retroviral compounds and may be an organic anion pump relevant to cellular detoxification. It is widely expressed, with particularly high levels in prostate, but is barely detectable in liver. It belongs to the ATP binding cassette (ABC) transporter family. MRP4 confers resistance to topotecan and acts as a double agent in protecting the brain from chemotherapy.
FACS: Use at a dilution of 1/20 - 1/50. ICC: Use at a dilution of 1/20 - 1/50. IHC-Fr (acetone fixed): Use at a dilution of 1/20. WB: Use at an assay dependent dilution. Predicted molecular weight: 159 kDa. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user.
Type: Primary
Antigen: MRP4
Clonality: Monoclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rat
Isotype: IgG2a
Reactivity: Human