To order chemicals, medical devices, or other restricted products please provide ID that includes your business name & shipping address via email [email protected] or fax 484.881.5997 referencing your VWR account number. Acceptable forms of ID are:
- • State issued document with your organization's Federal Tax ID Number
- • State issued document with your organization's Resale Tax ID Number
- • City or County issued Business License
- • State Department of Health Services License
- • Any other ID issued by the State that includes the business name & address
* ATTN: California Customers may require additional documentation as part of the CA Health & Safety Code. Products that fall under this regulation will be placed on a mandatory 21-day hold after documentation is received. VWR will not lift restrictions for residential shipping addresses.
Spécifications
- Antibody type:Primary
- Antigen name:Calcitonin-related Polypeptide Alpha
- Clonality:Monoclonal
- Clone:6F10
- Gene ID:796
- Host:Mouse
- Isotype:IgG1
- Reactivity:Human
- Antigen symbol:CALCA
- Conjugation:Unconjugated
- ELISA:Yes
- Size:100 μg
- Western blot:Yes
- Antigen synonyms:CT|Calcitonin-related Polypeptide alpha|CGRP|CALC1|KC|CGRP1|CGRP-I|Calcitonin
- Storage buffer:Preservative: 0.1% Sodium Azide; Constituents: PBS
- Storage temperature:Store at 4°C
- Concentration:2.5 mg/ml
- Immunogen:N-terminal fragment (purified) (Human) (see figure).
- Tested applications:Electron Mobility Shift Assay, Enzyme Immunoassay
- Purification:Protein A purified
- Cat. no.:89350-914
- Supplier No.:GTX14816
Spécifications
A propos de cet article
Procalcitonin (PCT) is a 116 amino acid residue peptide with molecular weight of about 13 kDa. The amino acid sequence of PCT was firstly described by Moullec et al. in 1984. It belongs to a group of related proteins including calcitonin gene-related peptides I and II, amylin, adrenomodulin and calcitonin (CAPA peptide family). PCT, like other peptides of CAPA family, appears from the common precursor pre-procalcitonin consisting of 141 amino acids by removal of 25 a.a.r. from N-terminus. PCT is produced normally in C-cells of the thyroid glands. It undergoes successive cleavages to form three molecules: N-terminal fragment (55 a.a.r.), calcitonin (32 a.a.r.) and katacalcin (21 a.a.r.). It has been shown that the level of PCT in serum increases significantly during an infection of bacterial origin (Assicot M, et al). Today PCT is considered to be one of the earliest and most specific markers of sepsis. However, several studies revealed that elevated PCT level in human blood could be detected not only in case of sepsis and infection, but also in cases of surgery, polytrauma, heat shock and cardiogenic shock (Meisner M. & Reinhart K). The importance of PCT measurements in combination with cTnT or cTnI during heart transplantation to predict an early graft failure has been proved(Potapov EV., et al).
ELISA: Use at an assay dependent dilution. EIA: Use at an assay dependent dilution. WB: Use at an assay dependent dilution. Predicted molecular weight: 13.9 kDa. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user.
Type: Primary
Antigen: CALCA
Clonality: Monoclonal
Clone: 6F10
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype: IgG1
Reactivity: Human