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Spécifications
- Antibody type:Primary
- Antigen name:Lysosomal-associated membrane protein 2
- Clonality:Monoclonal
- Clone:GL2A7
- Gene ID:3920
- Host:Rat
- Isotype:IgG
- Reactivity:Mouse
- Antigen symbol:LAMP2
- Conjugation:Unconjugated
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- ImmunoPrecipitation:Yes
- Size:100 μl
- Antigen synonyms:LAMP-2|LGP-B|Lysosome-associated membrane protein 2|CD107 antigen-like family member B|LAMP2|Lysosome-associated membrane glycoprotein 2|CD107b|Lysosomal membrane glycoprotein type B
- Storage buffer:Pure ascites.
- Storage temperature:Keep as concentrated solution. Store at 4 °C short term. For extended storage aliquot and store at –20 °C or below. Avoid freeze-thaw cycles.
- Immunogen:Purified preparation of mouse liver lysosomal membranes.
- Tested applications:ICC/IF, IP
- Purification:Unpurified
- Cat. no.:89359-724
- Supplier No.:GTX13524
Spécifications
A propos de cet article
Lysosomes are membrane-bound vacuoles which play a critical role in cellular metabolism. These organelles participate in endocytosis, the synthesis and assembly of acid hydrolases, act as sites for digestion of foreign materials and for specialized autolytic cellular processes. Membrane-associated glycoproteins have an important role in normal lysosomal function. Prior to posttranslational modification, Lysosome Associated Membrane Protein 2 (LAMP 2) is an ~45 kDa polypeptide. Mature, functional LAMP 2 is extensively glycosylated with a variety of different N-linked and O-linked oligosaccharides with a total molecular weight of ~100-110 kDa. LAMP 2 has a structure comprised of a large amino-terminal intra-lysosomal domain, a hydrophobic trans-membrane domain, and a short carboxyl-terminal cytoplasmic tail.
ICC: Use at a dilution of 1/100. The antibody will label the presumptive lysosomes and late endosomes in cells that have been permeabilized with saponin. IP: Use at an assay dependent dilution. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user.
Type: Primary
Antigen: LAMP2
Clonality: Monoclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rat
Isotype: IgG
Reactivity: Mouse